ID C1E209_MICCC Unreviewed; 467 AA.
AC C1E209;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=KH domain-containing protein {ECO:0000313|EMBL:ACO61838.1};
GN ORFNames=MICPUN_57067 {ECO:0000313|EMBL:ACO61838.1};
OS Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO61838.1, ECO:0000313|Proteomes:UP000002009};
RN [1] {ECO:0000313|EMBL:ACO61838.1, ECO:0000313|Proteomes:UP000002009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
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DR EMBL; CP001324; ACO61838.1; -; Genomic_DNA.
DR RefSeq; XP_002500580.1; XM_002500534.1.
DR AlphaFoldDB; C1E209; -.
DR STRING; 296587.C1E209; -.
DR GeneID; 8242188; -.
DR KEGG; mis:MICPUN_57067; -.
DR eggNOG; KOG1676; Eukaryota.
DR eggNOG; KOG1882; Eukaryota.
DR InParanoid; C1E209; -.
DR OMA; EETIPCA; -.
DR OrthoDB; 9299at2759; -.
DR Proteomes; UP000002009; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00105; KH-I; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR23308:SF53; KANADAPTIN-RELATED; 1.
DR PANTHER; PTHR23308; NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00013; KH_1; 2.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00322; KH; 2.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50084; KH_TYPE_1; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002009};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 372..436
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 1..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 184..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..93
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..311
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 467 AA; 51559 MW; B2B106535B6E8C29 CRC64;
MGDDAQVKEE EGMSPPRGQS RSRSRSRSPR RRSYSPDRRR RRDSRDRSRS RSRGRGRSWS
RSRSRSPRGY RRRSRSYSRS RSRSRSPPRR RRRSPPRGER DSRRPPPGGP ARVKAEAEEA
IPCVGYEGRI IGRGGETIRR IQEETGARIS IDRASGECMV SGSTEQVILG SAAVKKIIAE
AGERGGGGGG NGGGGGGFRP PSGPFEAEET IPCAGSEGRV IGKGGETIRR LQEETGCRID
IEKGSGLCTI KGTVAAVRAA AAAVRRQIED GDGGGGGFKR KRDSEDEPID SAAYGRELAQ
REEDDEPKPP PIEPDFGLSG ALAAETNTVN GVTLVYTEPL EAKKPTVRWR LYVFKNGELQ
GDPLKIHQQS YYLLGRERKV VDIPTDHPSC SKQHAVIQFR ARDVMDDDTG DMVQVVTPYI
LDLDSTNGTH LNGERIDPRK YYQLLEKDTL VFGQSTREFV ILNEDSK
//
