ID C1E8I5_MICCC Unreviewed; 428 AA.
AC C1E8I5;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Major facilitator superfamily {ECO:0000313|EMBL:ACO64158.1};
GN ORFNames=MICPUN_59386 {ECO:0000313|EMBL:ACO64158.1};
OS Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO64158.1, ECO:0000313|Proteomes:UP000002009};
RN [1] {ECO:0000313|EMBL:ACO64158.1, ECO:0000313|Proteomes:UP000002009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion
CC cotransporter (TC 2.A.1.14) family. {ECO:0000256|ARBA:ARBA00024362}.
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DR EMBL; CP001327; ACO64158.1; -; Genomic_DNA.
DR RefSeq; XP_002502900.1; XM_002502854.1.
DR AlphaFoldDB; C1E8I5; -.
DR GeneID; 8244188; -.
DR KEGG; mis:MICPUN_59386; -.
DR eggNOG; KOG2532; Eukaryota.
DR InParanoid; C1E8I5; -.
DR OMA; PKKERGT; -.
DR OrthoDB; 296987at2759; -.
DR Proteomes; UP000002009; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11662:SF399; GH23975P; 1.
DR PANTHER; PTHR11662; SOLUTE CARRIER FAMILY 17; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002009};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..424
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 428 AA; 44593 MW; 854BB48A3A5B3A39 CRC64;
MNDAAPIKST ARLSPDARRV VLLCAVTMLL ASADRTIFSL GSLAIARDLS LSMSTVGLLQ
SAFFWGYGVT QILGGVAADR FGGAKVLLAG LGLWSVGVAM IPAATLTPTP VAVIVAARVL
FGAASGCVMP ASAAAVALSV PAERRSSSLS LIFTFFNCGS AFGLLLAGSL IQTVGWKAVF
LAFGAVGVAW SAIGLATVPE SAKKGKVRQS SSRGSEREGD DGRPGGWLSL PGWMYPQLGA
LAWCHVCINW GFFILQSWLP VYLAKELGFS LGGSGLASAL PWFLTAACSF SSGQIADILV
ARGWERWKVR RLMMNIATVG PATALMLLPA ARSPVVAVFL LAVMLGTQAV SIAGYHSYLQ
DVLPSRAGSF LGMTNTLGVI AGIVANLFVG YVVETTGGFR LVFLVTALVY ASSGVVWNLS
ARGRVMFA
//
