ID C1EC38_MICCC Unreviewed; 958 AA.
AC C1EC38;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=MICPUN_61281 {ECO:0000313|EMBL:ACO65831.1};
OS Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO65831.1, ECO:0000313|Proteomes:UP000002009};
RN [1] {ECO:0000313|EMBL:ACO65831.1, ECO:0000313|Proteomes:UP000002009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC {ECO:0000256|ARBA:ARBA00006489}.
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DR EMBL; CP001329; ACO65831.1; -; Genomic_DNA.
DR RefSeq; XP_002504573.1; XM_002504527.1.
DR AlphaFoldDB; C1EC38; -.
DR STRING; 296587.C1EC38; -.
DR GeneID; 8246438; -.
DR KEGG; mis:MICPUN_61281; -.
DR eggNOG; KOG2106; Eukaryota.
DR InParanoid; C1EC38; -.
DR OMA; ICCADFH; -.
DR OrthoDB; 294256at2759; -.
DR Proteomes; UP000002009; Chromosome 9.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR005108; HELP.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF33; HELP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF03451; HELP; 1.
DR Pfam; PF00400; WD40; 5.
DR SMART; SM00320; WD40; 10.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002009};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 169..204
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REPEAT 638..680
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 722..754
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 875..917
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 17..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 142..172
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 26..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 958 AA; 104839 MW; DB4E3DED768DC2A4 CRC64;
MEDVLRADYG DAAQKALNDA ARAKSKPSST ARRERALAPE LPAMERDKPY RPPFWESKKF
GEPYGDFNRV AKPKAVVVVP KPPAGVPTTD LKGRPVLRDN ATMRASGKLS TGKTAPVAAL
AKKTGRLSVK EEEAVDAAYR HNLAVGNRLQ ELEEQMRSAL KARRQLHCAE RELLTNAFAR
VDPDKTRVVS VERFVEVWKS FGVEVTDREA RAAFNKYGQT RDGSLPYPVF TEALLVGKAR
LVGMSSEVRR GAFPLNRPAE EYQFHGKILY PQCRKGVFTP SGWDGSPARR SCKAPDATME
LTWVHGYARD CLANNLFYTA TGDIVYFTAA LGIVYDKDAH SQRFFTGHDD DVKCLAISNA
RDLCASGQVG KYPYVCVWDP ATCEEKKKLR HPAVRGIAAV DFCRDAKLLA SVGMDNNHTI
FVWDWRAGKC AHEVKGHTDV PPKVYGIAFD PFGPDPTAFL SYGVNHIKWW SKPEGSKTYT
EESGKFAPAA KKHAVMSAAW LPSGRCVTGT PDGAIAVWDS RDRKCVRVVR AHAAGPQVTR
EDGPPTHHGV RCLRLRADQK TLLSAGADGH VISWDVSSGD LKEGSVLGAV PVKRRSGSDA
PHPPVFRGLD CAPGSDVFVA GTHRSEVWEI DDTPRVLIHG HSADLYGVAW NPAAPTEFAT
ASEGEHVHVW CAASRKLQRT VALGSKARCV GYSPDGGELA VGCKNGGVHV LDAKSLIRLK
WMKTLAEYVT DVKFSPDGEL LAAASADQRI DVYERKGGYK KIATCRGHSA TVRHVDWCAE
SKILRTVCGA YEILYFDART GRQVTANQRD TKWATWTSVL GFDVMGIWRD GSDGTDINAC
DVSKSRRHVA CADDFGGVSL LNYPCVVEDA PCAVGRGHSS HVMNVRFSPD DDWVVSVGGK
DRAVFQWRFR EKTREIPKTA PAPWEAAEAE LRGKARGAAA PGGTRGAAPW ETPPALKQ
//
