ID C1EC64_MICCC Unreviewed; 434 AA.
AC C1EC64;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Methyltransferase domain-containing protein {ECO:0000259|Pfam:PF13847};
GN ORFNames=MICPUN_61308 {ECO:0000313|EMBL:ACO65846.1};
OS Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO65846.1, ECO:0000313|Proteomes:UP000002009};
RN [1] {ECO:0000313|EMBL:ACO65846.1, ECO:0000313|Proteomes:UP000002009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. gTMT family. {ECO:0000256|PROSITE-ProRule:PRU00914}.
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DR EMBL; CP001329; ACO65846.1; -; Genomic_DNA.
DR RefSeq; XP_002504588.1; XM_002504542.1.
DR AlphaFoldDB; C1EC64; -.
DR STRING; 296587.C1EC64; -.
DR GeneID; 8246453; -.
DR KEGG; mis:MICPUN_61308; -.
DR eggNOG; KOG1269; Eukaryota.
DR InParanoid; C1EC64; -.
DR OMA; ATWCQRD; -.
DR OrthoDB; 2249143at2759; -.
DR Proteomes; UP000002009; Chromosome 9.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009820; P:alkaloid metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR025774; MTs_g-TMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR44068:SF11; GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR44068; ZGC:194242; 1.
DR Pfam; PF13847; Methyltransf_31; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51581; SAM_GTMT; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00914};
KW Reference proteome {ECO:0000313|Proteomes:UP000002009};
KW S-adenosyl-L-methionine {ECO:0000256|PROSITE-ProRule:PRU00914};
KW Transferase {ECO:0000256|PROSITE-ProRule:PRU00914}.
FT DOMAIN 196..318
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13847"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..207
FT /note="SAM motif I"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00914"
FT REGION 262..270
FT /note="SAM motif II"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00914"
FT REGION 289..298
FT /note="SAM motif III"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00914"
SQ SEQUENCE 434 AA; 47085 MW; BDC838340896387D CRC64;
MLGGSPGIRT SPTARSARRA RPVAVAARSD AGSNVPGALS VADLAAPVLK SHGKTVANEI
ALVSAKSAAV VAKDPAKAPA PTVAGLPVTH VAGGALAAAG AALALKNIFD RPSRAYVSGP
EDGGLGTVGE EYDAWTEEGI LEYYWGEHIH LGWYSDEDMA KGAGTLLGSN VKNFIEAKFD
FVDKMLEWSE CPPEPARVLD VGCGIGGTSR HLAKRLGPNS QVQGITLSPN QVKRATELAA
EQGVPNAKFQ VMNALAMDFP DDTFDLVWAC ESGEHMPDKK KYVEEMIRVL KPGGTIVIAT
WCQRETPPEF TDVEKANLKF LYEEWAHPYF VSIEEYVRLM EGTDKMATVG SANWVKNTIR
SWRHSIWVGV WDPWPVVFKG PRIWYKTIRE IVTLERMHRA FDCDLMTYGM MKGKKKPAAT
VNAASDTVAV GSEK
//
