ID C1EEU4_MICCC Unreviewed; 567 AA.
AC C1EEU4;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=beta-ketoacyl-[acyl-carrier-protein] synthase I {ECO:0000256|ARBA:ARBA00013191};
DE EC=2.3.1.41 {ECO:0000256|ARBA:ARBA00013191};
GN ORFNames=MICPUN_62746 {ECO:0000313|EMBL:ACO66592.1};
OS Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO66592.1, ECO:0000313|Proteomes:UP000002009};
RN [1] {ECO:0000313|EMBL:ACO66592.1, ECO:0000313|Proteomes:UP000002009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; CP001330; ACO66592.1; -; Genomic_DNA.
DR RefSeq; XP_002505334.1; XM_002505288.1.
DR AlphaFoldDB; C1EEU4; -.
DR STRING; 296587.C1EEU4; -.
DR GeneID; 8247464; -.
DR KEGG; mis:MICPUN_62746; -.
DR eggNOG; KOG1394; Eukaryota.
DR InParanoid; C1EEU4; -.
DR OMA; ESTICPV; -.
DR OrthoDB; 546841at2759; -.
DR Proteomes; UP000002009; Chromosome 11.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 2.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002009};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 91..561
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT REGION 48..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 567 AA; 57338 MW; 5525FB0D240B42EF CRC64;
MALGARATSA SRVVGDAARA VADHSSFILA PSRCRGCTDA GHASRRFASS TASSSSSSSS
SSSSPPRRGW GDDDDRGTAL GFDHPPPVRA PRRVVVTGIG LATPLGVGTS LVWERLLAGR
SGIRELTPDD IPEGERGYEQ MPIRIGARVP RVGGRRDEPN ADADAGAFDA TRWCGGDVFG
VASASHSSPS RTDAARPAVG GGPRIAPFTG LALAAAHEAL QDARWDPSAT GATRPDRCGV
FIGAGMGHVP DLTNAGALLE RGKLRRVSPF FVPRILCNMA AGHVSMAHGF TGMNHAVATA
CASGAHAIGD AYRAVARGDV DLVLAGGAES AIDAVSFAGF ARARALADPA KFPPNLAVDP
AAVCRPFDAR RGGFVMGEGS GVLVLESLES AIARGVAPYA EVRGYGCAAD AHHITQPPRD
GDGAALAMLN ALADGGIEPG CVGYVNAHAT GTTTGDAAEA KALSRVFGKA LATGTTRVSS
TKGATGHLLG AAGAVEAAFA VLSIASGDCP PTLNLDDPCG ECVPDGADFV ARVAARGARP
RAAMSNSFGF GGTNASLVFA APPRLRG
//
