ID C1EIB1_MICCC Unreviewed; 644 AA.
AC C1EIB1;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51193};
DE Flags: Fragment;
GN ORFNames=MICPUN_88790 {ECO:0000313|EMBL:ACO67649.1};
OS Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO67649.1, ECO:0000313|Proteomes:UP000002009};
RN [1] {ECO:0000313|EMBL:ACO67649.1, ECO:0000313|Proteomes:UP000002009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
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DR EMBL; CP001333; ACO67649.1; -; Genomic_DNA.
DR RefSeq; XP_002506391.1; XM_002506345.1.
DR AlphaFoldDB; C1EIB1; -.
DR STRING; 296587.C1EIB1; -.
DR GeneID; 8249503; -.
DR KEGG; mis:MICPUN_88790; -.
DR eggNOG; KOG1132; Eukaryota.
DR InParanoid; C1EIB1; -.
DR OMA; ICETETF; -.
DR OrthoDB; 124793at2759; -.
DR Proteomes; UP000002009; Chromosome 15.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd17970; DEAHc_FancJ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR013020; Rad3/Chl1-like.
DR NCBIfam; TIGR00604; rad3; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF34; REGULATOR OF TELOMERE ELONGATION HELICASE 1; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002009}.
FT DOMAIN 15..314
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT REGION 73..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 644
FT /evidence="ECO:0000313|EMBL:ACO67649.1"
SQ SEQUENCE 644 AA; 69473 MW; AF38650F1EEC460B CRC64;
MPTYGLKVKG RGEEVTYSVD FPYDAYDCQV TMMERVVEAL HAGENALLES PTGTGKTLCL
LCAALGWREK AHAGGGPDDV TVGPDARAAA AARGDDRAPD RGPLIVYASR THSQLAQVIR
ELRATRYRPR MAIMGSRQQM CVHKDVRVLA GAAQNAACKA RTQSRSCAHH NELEHFRRRE
PNFGRDDPVD IEDLVKLGER GVVGGGCGPC PYFMSLDMYK EADIVFMPYN YVVDPAMRDV
LGDRLDGAIV LFDEAHNIES VCSDAAGFDI PASHLAQAIN EAQEAFEAAG ADPGADARKP
PRPAAEYKQL RGVLLALEDK VAAQVGNNGE ECVKPGEWLF ELLASLKITE QTLEMIKSIA
QDAASLLAGE AAAVGQRSRA RASGYRINEL AEALELAFRA RREGHVGSFR LRIGADESRG
GFGAGHGAGP TLSFWCFSPS VTMSHLAEKG VKSVILTSGT LSPMSSFASE LGLNFRVRLE
NPHVVAPHQV WGGVVPVGPS GKRLNSTYRF RDTDEYKSEL GNVVVNFARI VPDGMLVFFP
SYGVMRACVE HWRNTGTPSI WERICASKHA VVEPSGKEEF REAFKEFNDA LEATPGGGAG
GRNGAAFFAV CRGKVSEGID FADKAGRCVV LTGIPYAPKA DAKV
//
