ID C1F8H8_ACIC5 Unreviewed; 637 AA.
AC C1F8H8;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Succinate dehydrogenase or fumarate reductase, flavoprotein subunit {ECO:0000313|EMBL:ACO31853.1};
DE EC=1.3.99.1 {ECO:0000313|EMBL:ACO31853.1};
GN Name=sdhA {ECO:0000313|EMBL:ACO31853.1};
GN OrderedLocusNames=ACP_0102 {ECO:0000313|EMBL:ACO31853.1};
OS Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / BCRC 80197 / JCM
OS 7670 / NBRC 15755 / NCIMB 13165 / 161).
OC Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC Acidobacterium.
OX NCBI_TaxID=240015 {ECO:0000313|EMBL:ACO31853.1, ECO:0000313|Proteomes:UP000002207};
RN [1] {ECO:0000313|EMBL:ACO31853.1, ECO:0000313|Proteomes:UP000002207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51196 / DSM 11244 / BCRC 80197 / JCM 7670 / NBRC 15755 /
RC NCIMB 13165 / 161 {ECO:0000313|Proteomes:UP000002207};
RX PubMed=19201974; DOI=10.1128/AEM.02294-08;
RA Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M.,
RA Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B.,
RA Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C.,
RA Davidsen T.M., DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S.,
RA Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P.,
RA Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q.,
RA Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R.,
RA Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R.;
RT "Three genomes from the phylum Acidobacteria provide insight into the
RT lifestyles of these microorganisms in soils.";
RL Appl. Environ. Microbiol. 75:2046-2056(2009).
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DR EMBL; CP001472; ACO31853.1; -; Genomic_DNA.
DR RefSeq; WP_012680510.1; NC_012483.1.
DR AlphaFoldDB; C1F8H8; -.
DR STRING; 240015.ACP_0102; -.
DR KEGG; aca:ACP_0102; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_014312_7_0_0; -.
DR InParanoid; C1F8H8; -.
DR OrthoDB; 9806724at2; -.
DR Proteomes; UP000002207; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ACO31853.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002207}.
FT DOMAIN 36..441
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 502..636
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 330
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 637 AA; 70513 MW; 4C73A535BAA64DF1 CRC64;
MTLDANIPSG PIEQAWDKAR FDMKLVNPAN KRKHTVLVVG SGLAGASASA SMGELGYNVK
CFCFQDSPRR AHSIAAQGGI NAAKNYQNDG DSVYRLFYDT VKGGDFRSRE ANVYRLAQNS
VNIIDQCVAQ GVPFAREYGG ALTNRSFGGA QVSRTFYARG QTGQQLLLGA YQALERQIQA
GTVKMFPRTE MLDLIVVDGH ARGIVTRHLV TGEISVHFGD AVVLASGGYG NVYYLSTNAK
GSNVTASWRA HKRGALFANP CFTQIHPTCI PVSGDYQSKL TLMSESLRND GRIWVPKQKG
DKRPPSQIPA EERDYYLERR YPSFGNLVPR DVASRNAKHV CDEGRGVGET GLGVYLDFSD
AIQRLGENVI RERYGNLFDM YQRITDENPY KVPMRIYPAI HYTMGGLWVD YYLQSTIPGL
FVAGEANFSD HGANRLGASA LMQGLSDGYF IIPYTVGNYI ANHKLDKVDE SHPAVKEAVG
GVEQSISKLL SIKGKRTVDS FHRELGKIIW DECGMSRTAQ GLEKGIQQVR ALREEFWQNV
NVPGSGSDLN QSLEKAGRVA DFFELGELMC IDALNRNESC GGHFREEYQT PDGEAKRDDE
NYSYVAAWGY NGPNGAPTLT KEPLEFEYVH PSQRSYK
//
