ID C1FGI8_MICCC Unreviewed; 639 AA.
AC C1FGI8;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=DNA polymerase II subunit 2 {ECO:0000256|ARBA:ARBA00032930};
GN ORFNames=MICPUN_101999 {ECO:0000313|EMBL:ACO69553.1};
OS Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709) (Picoplanktonic
OS green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=296587 {ECO:0000313|EMBL:ACO69553.1, ECO:0000313|Proteomes:UP000002009};
RN [1] {ECO:0000313|EMBL:ACO69553.1, ECO:0000313|Proteomes:UP000002009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC299 / NOUM17 {ECO:0000313|Proteomes:UP000002009};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC {ECO:0000256|ARBA:ARBA00009560}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001575; ACO69553.1; -; Genomic_DNA.
DR RefSeq; XP_002508295.1; XM_002508249.1.
DR AlphaFoldDB; C1FGI8; -.
DR STRING; 296587.C1FGI8; -.
DR GeneID; 8245643; -.
DR KEGG; mis:MICPUN_101999; -.
DR eggNOG; KOG3818; Eukaryota.
DR InParanoid; C1FGI8; -.
DR OMA; DCYHIED; -.
DR OrthoDB; 166885at2759; -.
DR Proteomes; UP000002009; Chromosome 8.
DR GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR016266; POLE2.
DR PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 2.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002009}.
FT DOMAIN 272..433
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
FT DOMAIN 542..601
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
FT REGION 446..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..546
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 70077 MW; 94AE67B2D8323B28 CRC64;
MAAVVDFLER CDDPHAALSQ MLDELDAKAL TTSIVDLRCA EEVIHAVDKH NGTGAFAAPD
GQGTAALLDD EDGITIVDAF DMPRYCYDTQ RKVFHENAGK VKTINASAES KIELYRERFL
LLQQRVARHR MFVKPAFSAS GAAAQRTYCE LTPLTGLLGH SVGTKYVMGC LSQLEDDRFF
LEDLTGQIQV DVSHAATSSG LYTENCIVVA EGEVRKSDGV LEVRALGFPP AESREDTRNA
TNFLDFVGAG RLRPKDIERM VEEEAASTSD MFVVLSDVWL DRESTFARLR TVFEGFDSLD
AIPSMFVLMG DFSSQPFGPT RFGFGDYAKG FDKLAELVRE FPRLRQEARW VIVPGPGDPG
VSSALPRPPL MPSLTESLRE ALPRATFASN PARVRYRSQD LVFMREDLQS RMRRNCILPP
TEIEDAPAEK AARARARAKA LARQARLERN EARAERRAAA RAKKLRGGKG GGKGGVVGGG
GAGSGDENAE PNGATAEDLF DAVMEEADGG ADVDADVDAD GDDGEEIVSD DELSEEEEEE
DEEASEWENR PLFRHLAATL VQQAHLAPLP IAQLPVYWEH DHALRLYPAP HCVVLGDRTE
QQALAKFEDT ELVNPGCFAD DGSFAVYRPA TREVEFSAV
//
