ID C1G7Z4_PARBD Unreviewed; 1450 AA.
AC C1G7Z4;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 2.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Pectate lyase superfamily protein domain-containing protein {ECO:0000259|Pfam:PF12708};
GN ORFNames=PADG_03299 {ECO:0000313|EMBL:EEH47201.2};
OS Paracoccidioides brasiliensis (strain Pb18).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502780 {ECO:0000313|EMBL:EEH47201.2, ECO:0000313|Proteomes:UP000001628};
RN [1] {ECO:0000313|EMBL:EEH47201.2, ECO:0000313|Proteomes:UP000001628}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pb18 {ECO:0000313|EMBL:EEH47201.2,
RC ECO:0000313|Proteomes:UP000001628};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; KN275959; EEH47201.2; -; Genomic_DNA.
DR RefSeq; XP_010758345.1; XM_010760043.1.
DR STRING; 502780.C1G7Z4; -.
DR GeneID; 22582632; -.
DR KEGG; pbn:PADG_03299; -.
DR VEuPathDB; FungiDB:PADG_03299; -.
DR eggNOG; ENOG502SINF; Eukaryota.
DR HOGENOM; CLU_004874_0_0_1; -.
DR InParanoid; C1G7Z4; -.
DR OMA; YHAFTPF; -.
DR OrthoDB; 3714838at2759; -.
DR Proteomes; UP000001628; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0004650; F:polygalacturonase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08621; PI-PLCXDc_like_2; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 2.
DR InterPro; IPR024535; Pectate_lyase_SF_prot.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR InterPro; IPR039279; QRT3-like.
DR PANTHER; PTHR33928:SF2; PECTATE LYASE SUPERFAMILY PROTEIN DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR33928; POLYGALACTURONASE QRT3; 1.
DR Pfam; PF12708; Pectate_lyase_3; 2.
DR SUPFAM; SSF51126; Pectin lyase-like; 2.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001628};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1450
FT /note="Pectate lyase superfamily protein domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002909856"
FT DOMAIN 196..426
FT /note="Pectate lyase superfamily protein"
FT /evidence="ECO:0000259|Pfam:PF12708"
FT DOMAIN 566..628
FT /note="Pectate lyase superfamily protein"
FT /evidence="ECO:0000259|Pfam:PF12708"
FT REGION 97..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 946..974
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 63..90
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1450 AA; 159783 MW; 4626A3A931402C34 CRC64;
MATRSHGLLQ ALLIWTLLSL QILASVMSPV LINPLRNAHE NKMHDLVPRN QLGTNVVLPP
SVAKATQLDI DEARRIVDDA IKEASALNKA RLEHPLRNHY QLKPGTGTSR RGEPNGDAPP
PPLFQISKEI AAAAALIAEV EAVAETRDSS KSKADYSYID VMYNRTVVRR ADAFWMEDIE
RKGAWPFGND RSFKVFRNVK DYGAVGNGVN DDTEAIKRAI ADTGTCGEKC NGATTKNSIV
YFPSGTYLVS STIETHFGSQ VIGNANDRPV IKAASSFIGL GVLSTNHYVE NGGNGTDGNA
KEWYVNTANF YRQIRNFRID ITATNQGAYI AALHYQVAQA TSLSNIDFIV SSNPGTTQQA
IFSENGSGGI LSDLTFTGGN FGIYGGNQQF TAQRLQFTNC KTAVQLIWDW GWIWKNIQIT
GSTTGFKLMS EDNVPRSGSI MVLDSIFRNT DTALLTFPAK QERAKGTTGI TLDNVAFDKV
RNAVADNQGK VYLAGSVGSI NTWALGPVYF DSSQRDFTLG MSFDTSREST LLADRLSALP
KAPFFERPRP QYEGVPVSDF VHMKDYAKGD GVTDDTEAFQ RVLREHSTDR IIFVDAGSYI
LTDTIIIPVG ARIVGEGWSQ LVASGPNFQD ERAPRSLVLV GQPGDTGEVE IQDLLFTTKG
PTAGAVLVEW NIKASSPGSA GMWDSHVRIG GASGTKLTST ECPAIRNGVN SDDCKSGSLM
MHITESSSAY MENVWLWVAD HDIDDPHLQD DNNTMVQTSV YSARGLLVES AEATWLYGTS
SEHAIYYQYN FYKAKNVFAG MIQTESPYYQ PTPKPPAPFE GAIGVLPGDP DFGGCRDGTP
GCDASWGLRI INSSQTYIAG AGLYSWFTTY TQECVDKRNC QNALIELKGN GPRVRIHNLI
TIGATNMLTS DGSEVPSQDN LAVDYHPYWS QVTVIDPFQN RGARGLTTPT SPDKSGRQCP
NIPPEVNVPG GKYPPDIPVM GRPGKSDHGY FTLVNGSPYN WMLTYNHSYQ LDQWKWHNVP
AGESIQGEWK FARASNRYDD KGEAYYKIDG TDKSFQIWAR FYEDDPENAF HLRVLYDGLE
TKDVKRGTSL DYRTRGGYGG MRAINWVLTG SEEEGYWSSH SPPVAWMSSI LNIIGDRKVK
HVCMPGSHDA GMSKLDGHTQ FADEGNTLTQ YLSVYDQLRR GSRYFDVRPA IGNGGKYLTG
HYSYVDVLGI GWQGGNGESI QEIVDGINRF TAENPELIII NLDLTLDTDN GYKPFNDEQW
SKTFDLFEGV KYLQGNLEGD LTERTMNDYI GAGGAAVIVI ASGGPTRPEK GIYSNRQFPR
YDSYSNSDDP AAMADDQLAK LKGNRNIVSD TTERKDTFHI FSWTLTLSRV FERTIADQSI
ELGYDPLFWR GYHAFTPFSY PNVVYMDFIG SADQSETTLE KTHGEVTALA MAVNMELASR
NCYVGGGTMV
//
