ID C1GGW3_PARBD Unreviewed; 590 AA.
AC C1GGW3;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 07-JAN-2015, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Transcriptional repressor Tup1 N-terminal domain-containing protein {ECO:0000259|Pfam:PF08581};
GN ORFNames=PADG_06182 {ECO:0000313|EMBL:EEH50103.2};
OS Paracoccidioides brasiliensis (strain Pb18).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502780 {ECO:0000313|EMBL:EEH50103.2, ECO:0000313|Proteomes:UP000001628};
RN [1] {ECO:0000313|EMBL:EEH50103.2, ECO:0000313|Proteomes:UP000001628}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pb18 {ECO:0000313|EMBL:EEH50103.2,
RC ECO:0000313|Proteomes:UP000001628};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
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DR EMBL; KN275964; EEH50103.2; -; Genomic_DNA.
DR RefSeq; XP_010761638.1; XM_010763336.1.
DR AlphaFoldDB; C1GGW3; -.
DR STRING; 502780.C1GGW3; -.
DR GeneID; 22584969; -.
DR KEGG; pbn:PADG_06182; -.
DR VEuPathDB; FungiDB:PADG_06182; -.
DR eggNOG; KOG0266; Eukaryota.
DR HOGENOM; CLU_000288_57_23_1; -.
DR InParanoid; C1GGW3; -.
DR OMA; LTPDANW; -.
DR OrthoDB; 91476at2759; -.
DR Proteomes; UP000001628; Unassembled WGS sequence.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR013890; Tscrpt_rep_Tup1_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF748; TRANSCRIPTIONAL REPRESSOR TUP11; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF08581; Tup_N; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001628};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 15..83
FT /note="Transcriptional repressor Tup1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08581"
FT REPEAT 334..368
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 369..410
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 410..451
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 455..488
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 509..550
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 551..590
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 86..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..40
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 128..142
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..160
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 64134 MW; F063C925EBD8B773 CRC64;
MYNPHRGMVT APNSRLTELL DQLRQEYENQ SRNTGEFEHQ LTGQLQEMEM IRQKVYQLEQ
AQIKMKQEYE AEIRTLRMEL ESRGVHLPQS HIGGPPTHAG PSQAPPPALG HGPANLFGGI
MTNPGGGAPA LAPPPPPQDQ QQPPQHALQQ PGSGAQGPPQ PQQGAFGGYQ PASAVNGYGP
PPPAPTSSPG PGKGRASRAP PGPATPQQNH QVAYPDTRAS PQMPRPTPPG QQLSYRVGNT
LADLDPDKLP PSQKREGSDW YAVFNPEVPR LLDVDLVHHL VHDSVVCCVR FSNDGKFVAT
GCNRSAQIFD VQSGQLVTSL QDDSVLDKEG DLYIRSVCFS PDGRYLATGA EDKQIRVWDI
QKRTIKHIFS GHEQDIYSLD FARNGRYIAS GSGDKTVRLW DIVDGKQELI LSIEDGVTTV
AISPDGRFVA AGSLDKSVRV WDTTTGYLIE RLENPDGHMD SVYSVAFAPN GRDLVSGSLD
KTIKLWELTP PRGMVPGSGP KGGKCVRTFE GHKDFVLSVC LTPDGRWVMS GSKDRGVQFW
DPATGNAQMM LQGHKNSVIS VAPSPVGNLF ATGSGDMRAR IWRLVSTLNV
//
