ID   C1GK28_PARBD            Unreviewed;      1062 AA.
AC   C1GK28;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 2.
DT   24-JAN-2024, entry version 57.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   ORFNames=PADG_07614 {ECO:0000313|EMBL:EEH42794.2};
OS   Paracoccidioides brasiliensis (strain Pb18).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502780 {ECO:0000313|EMBL:EEH42794.2, ECO:0000313|Proteomes:UP000001628};
RN   [1] {ECO:0000313|EMBL:EEH42794.2, ECO:0000313|Proteomes:UP000001628}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pb18 {ECO:0000313|EMBL:EEH42794.2,
RC   ECO:0000313|Proteomes:UP000001628};
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
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DR   EMBL; KN275968; EEH42794.2; -; Genomic_DNA.
DR   RefSeq; XP_010762976.1; XM_010764674.1.
DR   AlphaFoldDB; C1GK28; -.
DR   STRING; 502780.C1GK28; -.
DR   GeneID; 22586077; -.
DR   KEGG; pbn:PADG_07614; -.
DR   VEuPathDB; FungiDB:PADG_07614; -.
DR   eggNOG; KOG1993; Eukaryota.
DR   HOGENOM; CLU_003886_1_0_1; -.
DR   InParanoid; C1GK28; -.
DR   OMA; SFHYVFH; -.
DR   OrthoDB; 6327at2759; -.
DR   Proteomes; UP000001628; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   PANTHER; PTHR10997:SF7; IMPORTIN-11; 1.
DR   PANTHER; PTHR10997; IMPORTIN-7, 8, 11; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001628}.
FT   DOMAIN          37..109
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   1062 AA;  119944 MW;  77AC7150F52C235C CRC64;
     MASVVELPGE ANPLTRQNIF NTLVNAAGNT QQQVVAGGQQ LQNWEKQPNY FSLLQDIFVD
     FSLPNEVRYL SIIQLKNGVD KYWRKTAPNA IKAEEKQQIR SRALEAGAVE PDTKLALHNA
     LMLAKIVRLE FPSEWPDAIV SVLTLLRAAC QPGSNPLQLP RTLLILLHIT KELSTVRLQR
     IKRNLYDIAP EIFHILANIY VEKVRKWGTF LEVGGDDEGG ALESFDESLI TLKTLRRLIV
     AAFENPNRDS DVQQFWTLSL AHVGNFYSLL ERKSSELAPN VTRLLERHIM QLSKLHLEMA
     KTHPAAFALF PGCVDLTRSY WGLVVELSKH YDPSDMSRAK IGTDGDADDE ETPFLENIAL
     KGLLILRSCI KMAFYPTHTF KYLHARDKEE RSQSIELIKS QLLTHEFVVQ VMELLITRFF
     VFRASDLRQW GEDPEEWEKR EDEITDAYDF SIRSCSDKVF LDLLIHFKQL LVPTLLRVFY
     SYASPQNQEV LLKDSLYSAV GLGAAILEKQ LDFNAFLSST LIPEVQIQQP GYNLLRRRIA
     ILLGQWVPVK ADELDMSSIY QIFQHLLNKS DPINDQVVRV TAGRQLKNVL EPFEFSVDRF
     LPYATPILQS LMDLIGEVTL TETKMALVGT VRVAVVKMED HIAPYADQIV SLLPQLWEQA
     SKENLMKQAI LTLLSSLIHS MKQESVRYHQ IIIPLIQKSV DPESEALIYL LEEALDLWSA
     VLIQAPAPPS PDLLHLIPSL FPVLDIDTEC VRQALEVTES YILLSPQEVL SDNIRFRLLA
     SLEALLGSTT RQRLGVVPHL VEMLIRAIEF VNPGNEQAYT IVAKSLMDSS FLPTLLSGLH
     EAYEANLTTG PKKKSPAVSG VVETDYFSVL ARIALASPKI FISSASSSRE DHLSEEETVN
     WILMEWFSHF DNMGDINRKK LHALALTHLL SINGPSTPPP AYLLNHLQSY LVVWTDLIRE
     LSEGTSYDPN DPLGGDYLIV WNAGSATGEP DEKYQANEPP ETTRRRTWSN ADPIHKINLR
     HFVTENLRGV VGACGGIDKF RDEWLVNVDR EVVNGFGELG VL
//