ID C1GKZ1_PARBD Unreviewed; 430 AA.
AC C1GKZ1;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=G protein-coupled receptor GPR1 C-terminal domain-containing protein {ECO:0000259|Pfam:PF11970};
GN ORFNames=PADG_07998 {ECO:0000313|EMBL:EEH43178.1};
OS Paracoccidioides brasiliensis (strain Pb18).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502780 {ECO:0000313|EMBL:EEH43178.1, ECO:0000313|Proteomes:UP000001628};
RN [1] {ECO:0000313|EMBL:EEH43178.1, ECO:0000313|Proteomes:UP000001628}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pb18 {ECO:0000313|EMBL:EEH43178.1,
RC ECO:0000313|Proteomes:UP000001628};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN275969; EEH43178.1; -; Genomic_DNA.
DR RefSeq; XP_010763362.1; XM_010765060.1.
DR AlphaFoldDB; C1GKZ1; -.
DR STRING; 502780.C1GKZ1; -.
DR GeneID; 22586380; -.
DR KEGG; pbn:PADG_07998; -.
DR VEuPathDB; FungiDB:PADG_07998; -.
DR eggNOG; ENOG502RYZC; Eukaryota.
DR HOGENOM; CLU_027149_3_1_1; -.
DR InParanoid; C1GKZ1; -.
DR OMA; FWLQIGD; -.
DR OrthoDB; 2682754at2759; -.
DR Proteomes; UP000001628; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR022596; GPR1_C.
DR PANTHER; PTHR23112; G PROTEIN-COUPLED RECEPTOR 157-RELATED; 1.
DR PANTHER; PTHR23112:SF0; G-PROTEIN COUPLED RECEPTOR 157; 1.
DR Pfam; PF11970; GPR_Gpa2_C; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
PE 4: Predicted;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000001628};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 250..316
FT /note="G protein-coupled receptor GPR1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11970"
FT REGION 401..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 48790 MW; 82FB694BA95FCD08 CRC64;
MNLVSLLWTA SEVTPVSILN ARSLPPRRVT PLIIDPLPEE HRRGLIAVAS TSLLSTIATG
ALLIFVTYRL VFWRKYYSTY IGYNQYIILI YNLLLADFQQ AVGFLMALHW TVRDKISYDS
PICFLQGWLL QIGDPSSGLF VLAIAAHTFG IVLMGRKLSH RWFVACVCGV WAFALLLVLI
PTIQHGRHVY VPSGAWCWID ENYDADRLWT HYFWIFVSEF GSIMLYALLF FHLRHQVAQS
AILGRGQTDN LRRLKRVIGY MVLYPIAYIV LSLPLAAGRM ATARGQRLSV SYFCTAGAVI
ASSGFVDVIM YTVTRQALLI DSEPSNVDRF YNSQRVGHSH VTTVTADHKM SRLDNSILHR
RQMTETDTQH DREGSTDQIV QPVELSELGK VYQKTTIEIT TELADDTDAS PDSTLNEPRP
PPPSHRWERR
//
