ID C1GTY2_PARBA Unreviewed; 375 AA.
AC C1GTY2;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=FHA domain-containing protein {ECO:0000259|PROSITE:PS50006};
GN ORFNames=PAAG_01977 {ECO:0000313|EMBL:EEH39788.1};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH39788.1, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH39788.1, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
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DR EMBL; KN293995; EEH39788.1; -; Genomic_DNA.
DR RefSeq; XP_002796089.1; XM_002796043.2.
DR AlphaFoldDB; C1GTY2; -.
DR STRING; 502779.C1GTY2; -.
DR GeneID; 9099535; -.
DR KEGG; pbl:PAAG_01977; -.
DR VEuPathDB; FungiDB:PAAG_01977; -.
DR eggNOG; KOG1882; Eukaryota.
DR HOGENOM; CLU_022457_0_0_1; -.
DR OMA; ALQFRYV; -.
DR OrthoDB; 9299at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.200.20; -; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR23308:SF53; KANADAPTIN-RELATED; 1.
DR PANTHER; PTHR23308; NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1; 1.
DR Pfam; PF00498; FHA; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002059}.
FT DOMAIN 280..343
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 38..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..97
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..114
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 375 AA; 43713 MW; F39AC858DFFE6092 CRC64;
MKPPSNLSKR RHKSVFFASR CFSTPSYNRH CASRLEMPRY EENVRDRRRR LGTSHSPVHA
HSRRAKDDDD DDDDDDDDSY CRRFKDDRSD MKYSRWHARS PTRSPRREHR SYRRRSRSRD
HDDTPRRRDD SRSSAHRRRP KNRSEYDDGN RLSKSQRSVS SSRARSPPRQ RSRSLSPRFS
KRSKNPLPSQ KEAFSRTPID ATSITSTTFP EKEKPNFANT GLLAAETNTV KSTDGLTSVV
LKYHEPPEAR KPPARDPWRL YVFKGEDLLE TIPLGGRSCW LIGRERLVVD LPVDHPSCSK
QHAALQFRYV EKRNEYGDRD GRVRPYLIDL ESANGSTVNG ELSPKGRYME LMDKDVLKFG
FSTREYVLML PPSGR
//
