ID C1GYD8_PARBA Unreviewed; 586 AA.
AC C1GYD8;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=PAAG_03092 {ECO:0000313|EMBL:EEH41528.1};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH41528.1, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH41528.1, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
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DR EMBL; KN293999; EEH41528.1; -; Genomic_DNA.
DR RefSeq; XP_002794546.1; XM_002794500.2.
DR AlphaFoldDB; C1GYD8; -.
DR GeneID; 9097830; -.
DR KEGG; pbl:PAAG_03092; -.
DR VEuPathDB; FungiDB:PAAG_03092; -.
DR eggNOG; ENOG502S2JB; Eukaryota.
DR HOGENOM; CLU_014855_0_0_1; -.
DR OMA; FFVKHAD; -.
DR OrthoDB; 2735283at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR CDD; cd00821; PH; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR039712; Meu6.
DR InterPro; IPR039483; Meu6_PH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR42073; MEIOTIC EXPRESSION UP-REGULATED PROTEIN 6; 1.
DR PANTHER; PTHR42073:SF1; MEIOTIC EXPRESSION UP-REGULATED PROTEIN 6; 1.
DR Pfam; PF15406; PH_6; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000002059};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 65..192
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..261
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..333
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..395
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 586 AA; 62034 MW; 511A78CAD42ACAB4 CRC64;
MSEVRKPAEE IPVVASAVEP ATDATAAAAA TAATAASPTE TPTQTPAPAA DTAVAAEEPA
KEEVKPATDG VLGHKSPGLV KGFRFSKRFF WFSDDAVEVR QLTTYFQNEK LSIAHPTAAW
ASQTGKGLLF YAKRAEDKAT PTGIVNLADI SDIVKESGHE FQFKVAGHKH VFQAGSDDER
ASWIAALEAK AAEAKREKET VTSSEGYKAE LEKLTKPPVV AAAAPKKSLE KKEPAKAEEG
EERKEEEKKP EQKEKSRSQS RKRASIFGSF LGKKEEEKKE EKLEGKEEPE VVAPAVETSA
PVAEAAETPV PTPAAEEPKA EEKKPEAKPE SPTAGKTKRA SIFGNIFHKV SNQDKIEKDS
AVKSTETPVS STAPQLGDPV DASTSEPTKP ETVTAAAEPS QPAKEGEEPV ASPTSAKNSF
LNFIKKHDDK KEIKANDKVE KKSEEALEAS AVEATTSPAT KDKRRTSLFG TLGKKEKKPE
GTSDGEQAGD EEAKSKSSAS SPLPKLGGVF HRVSKPSKKD KETAPAATPS ESEPIPEGAE
KPEPVSKDSP AEPTAAVNGS EAPEEIKDDA AAVPAASSSQ PVQAAA
//
