ID   C1GZ41_PARBA            Unreviewed;       659 AA.
AC   C1GZ41;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   04-FEB-2015, sequence version 2.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=ATP NAD kinase {ECO:0000313|EMBL:EEH41864.2};
GN   ORFNames=PAAG_03785 {ECO:0000313|EMBL:EEH41864.2};
OS   Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS   brasiliensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH41864.2, ECO:0000313|Proteomes:UP000002059};
RN   [1] {ECO:0000313|EMBL:EEH41864.2, ECO:0000313|Proteomes:UP000002059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- SIMILARITY: Belongs to the NAD kinase family.
CC       {ECO:0000256|ARBA:ARBA00010995}.
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DR   EMBL; KN294000; EEH41864.2; -; Genomic_DNA.
DR   RefSeq; XP_002794192.2; XM_002794146.2.
DR   AlphaFoldDB; C1GZ41; -.
DR   STRING; 502779.C1GZ41; -.
DR   GeneID; 9097627; -.
DR   KEGG; pbl:PAAG_03785; -.
DR   VEuPathDB; FungiDB:PAAG_03785; -.
DR   eggNOG; KOG2178; Eukaryota.
DR   HOGENOM; CLU_008831_7_2_1; -.
DR   OMA; EHMLKYW; -.
DR   OrthoDB; 455155at2759; -.
DR   Proteomes; UP000002059; Partially assembled WGS sequence.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0019674; P:NAD metabolic process; IEA:InterPro.
DR   GO; GO:0006741; P:NADP biosynthetic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   HAMAP; MF_00361; NAD_kinase; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   InterPro; IPR002504; NADK.
DR   PANTHER; PTHR20275; NAD KINASE; 1.
DR   PANTHER; PTHR20275:SF0; NAD KINASE; 1.
DR   Pfam; PF01513; NAD_kinase; 1.
DR   Pfam; PF20143; NAD_kinase_C; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EEH41864.2};
KW   NAD {ECO:0000256|ARBA:ARBA00023027}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002059};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   REGION          1..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          88..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          177..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          595..659
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..58
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        177..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   659 AA;  72282 MW;  FAE49D205B02C9FC CRC64;
     MPASLFTHPA LSPENLQTIG EELNLPPPPT FENHQQQPNA ELASLEESEL DPASSSAASA
     CTLTAVSHSI LRDSPRKPDP LKLNNQIATR SNDQKKAGDA PSASFASQRE LNPPLPDSPA
     PLVSPAKSFL QHHKNSRSID SIPFQTIMKA LASKGNSSSG APLPLAASLA SLLSQSRNDG
     ANNSSRRLSG TFPGPSAYHE RTPSTARFPL KSPCFYHQRF DDAVNIEKVL EEIAADEWIS
     HSRLMQTATG VREVSKQLQR RPIKLAVKNV MIVTKARDNR LVHLTRDLAE WLLSTPRYGS
     DLGVNVYVDH KLQWSKRFDA PGLLAKEPRF EHMLKYWTPD LCWSSPETFD LVLTLGGDGT
     VLYTSWLFQR VVPPVLSFSL GSLGFLTNFE FDKYKEHLNQ IMGDVGMRVN LRMRFTCTVY
     RMDQRHGHLP GAVVEGEQFE VVNELVIDRG PSPYVSNLEL YGDNELLTVV QADGCIFSTP
     TGSTAYSLSA GGSLVHPSIP GILLTPICPH TLSFRPMVLS DAMLLRIAVP TASRSTAYCS
     FDGKGRIELC QGDYVTVEAS QYPFPTVVAG AGEWFESVRR ALRWNVRGAV QKGWNCDTEG
     QSTAPSVEDE EEEHWDIDPD TTTPLGTGTD SGLGPSEDGE SPGPDSMSPL RKQMGLFSL
//