ID C1H3T2_PARBA Unreviewed; 765 AA.
AC C1H3T2;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Protein CASP {ECO:0000256|ARBA:ARBA00018691};
GN ORFNames=PAAG_05425 {ECO:0000313|EMBL:EEH34376.1};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH34376.1, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH34376.1, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the CASP family.
CC {ECO:0000256|ARBA:ARBA00006415}.
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DR EMBL; KN294005; EEH34376.1; -; Genomic_DNA.
DR RefSeq; XP_002792696.1; XM_002792650.2.
DR AlphaFoldDB; C1H3T2; -.
DR STRING; 502779.C1H3T2; -.
DR GeneID; 9095933; -.
DR KEGG; pbl:PAAG_05425; -.
DR VEuPathDB; FungiDB:PAAG_05425; -.
DR eggNOG; KOG0963; Eukaryota.
DR HOGENOM; CLU_016758_1_0_1; -.
DR OMA; FAGYCFA; -.
DR OrthoDB; 1643779at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR012955; CASP_C.
DR PANTHER; PTHR14043; CCAAT DISPLACEMENT PROTEIN-RELATED; 1.
DR PANTHER; PTHR14043:SF2; HOMEOBOX PROTEIN CUT; 1.
DR Pfam; PF08172; CASP_C; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002059};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 691..710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 451..713
FT /note="CASP C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08172"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 739..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 160..241
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 266..300
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 341..368
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 428..483
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 547..595
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 9..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 765 AA; 85141 MW; A1ADAE573484B1CE CRC64;
MDALIASETV RDGSTSTENS PSGEPAKSEK QVREENKFQR AIAVWRGVDL ANLIPKLDTT
ASDIIAHQRD SLVQRKDLAQ KTKDFRKLDD STKLAEYKSL LKSYQTFIDL LTNHGKASSS
AFLQLYSALS EAPDPYPLLE ASVDSLVLSE DTVPKLTSEK ELLQKSVNRL TSQLEESEKK
LEDERSFRRK LEETQDTKIQ EIEASWAAVL AEKTSNWEAK EKNYEAKAEN HERLLKEIKA
SYEVNQRLDR ADGEDMSRSA ATAAELEIVA SELEKTSVRL AEVEARNEQL SLELAQAVSH
SQSEHRYHTL EDDPAFLRLQ SENSSLLRKL DSARYEKDAE RHSWEGKFRQ AERQNKKVTA
ERDEIKAKLD KWADYDDIRR ELEVIKSIEF YTADDDDRDA VDETDLVAFN GSERSKENTL
EQLLLTRNKK LSNELTILRV SHQDLQNQLE ALREDLSKTK VDLEKARNLA TTLENDLLQM
QREAPNLPSS AMSVAGPYVS RLPHPSRRGR ASPTSSIISG FDHANASANA IEAIRAGEAV
GGGSGILPMV QAQRDRFKQK NSELEEELSK TYAIVKSLRQ EVASLQKDNL SLYEKTRYVS
TYNRGRGDDL SASSASAYAN IPNATSVHLS AESPSGLSAD RYQSAYEAQI SPFAAFRGRE
SARAYRRMSV PERIIFSVTR MVLANRTSRN LFAGYCVALH VLLFVMLYMM STADIERKAA
GAALGSLGQA AAAGSVGAAA GTGRRAGGGP AGSEWRQETF NGPAQ
//
