ID C1H473_PARBA Unreviewed; 1510 AA.
AC C1H473;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 04-FEB-2015, sequence version 2.
DT 24-JAN-2024, entry version 81.
DE RecName: Full=PHD finger and BAH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PAAG_05566 {ECO:0000313|EMBL:EEH34517.2};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH34517.2, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH34517.2, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
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DR EMBL; KN294006; EEH34517.2; -; Genomic_DNA.
DR RefSeq; XP_015699844.1; XM_015845618.1.
DR AlphaFoldDB; C1H473; -.
DR STRING; 502779.C1H473; -.
DR GeneID; 9095745; -.
DR KEGG; pbl:PAAG_05566; -.
DR VEuPathDB; FungiDB:PAAG_05566; -.
DR eggNOG; KOG0955; Eukaryota.
DR HOGENOM; CLU_001514_0_0_1; -.
DR OMA; WVMDEPP; -.
DR OrthoDB; 1409291at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04710; BAH_fungalPHD; 1.
DR CDD; cd15571; ePHD; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR029617; Snt2.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR47672; E3 UBIQUITIN-PROTEIN LIGASE SNT2; 1.
DR PANTHER; PTHR47672:SF1; E3 UBIQUITIN-PROTEIN LIGASE SNT2; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00439; BAH; 1.
DR SMART; SM00249; PHD; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS51293; SANT; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002059};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 22..140
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 318..492
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 505..548
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT DOMAIN 773..823
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 882..999
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT REGION 411..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 712..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1082..1119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1222..1510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1258..1277
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1328..1346
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1361..1400
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1434..1449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1490..1510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1510 AA; 166828 MW; 1956F0BB463E1B77 CRC64;
MMSFNNCRAY LKQGKLIADD GTILSVNDHV YLVCEPPGEP YYLARIMEFL PSKDNPDGPI
ESIRVNWYYR PRDIHRKAAD LRVVFASMHS DTCPLSSLRG KCQIKHLSEI SNLDEFRKSK
DCFWFEKMYD RYIQRYYEVI PTTTVINVPQ HVKKVLDERW KYVLVELGRR KDLTSAVKTC
KKCSLYAANM DSVDCAVCHS TYHMYCVRPV LQKKPARGFA WACAACSRAQ ERKLEARNTP
IIGDASIETE PEVIEEEEED PAAHAEVTQR STPALPDIVR PATSEQIAQA KLWPFRYLGI
HCRVEDALDY DDRIYPRASS RIGPRHQANV IPWHGHPVQY VKTAEPRKKN VKSNNKKDLK
LSKEAVAAIE AEKAERAKRP KWIQDEPVGY IPRGEDEPVT VNGKQIRTAE LEFKMPEASQ
LPSRGEDDAS ETSLSDTDRE KFVDEYMAKA KEIAPSLKVE KYSTNFLDKA LALLYEENFN
VDAALAKLKR VNKYSDLKEP YLRPEEIKAF ESGVAKYGSE LRNVTKHVGT VPHRHIVRYY
YMWKKTEKGR QIWGNFDGRR GKKAAKQADN AVKLVDDVAD DHDDSAFDNE KAKDKKRGFT
CKFCSTRSSR LWRRAPGTPP GTTVPVDLKR DKAVQSLTVA ICSRCAVLWR KYGIQWEDAD
EVVKKIGQGG SKSWRRRYEE ELLVQLLTSS ETDVKINSTT AATATAMGIP VIADVNVPPP
PSEPPRKKAK SSLDQNGNAQ ATNTPADPVP KKKVVEKPAE PPPIAPEPPR VKTLPCAVCS
KMDPMGDQHL SCRDCRLTVH RACYGVNPSW NSSKWFCDMC SNDRNPVIST SYECVLCPVT
YTEHELMEPP RVSHKKKTDR EREKERLEKE MVAEASKLYK IRQKEAGKPT GPREPLKRTA
GNNWVHVTCA VWMPEIKFGN AKELEPAEGL GLVPAERYQD ICKICKTRQG ACVSCHNTSC
NARFHVGCAH QSGYIFGFDI TPVKSSRRDA VHMMKLGDEA GAVTPAIWCP HHTISTVVHE
MSEPSEIQGL NALQLYCQTS KQADLTLTGT VRKAAHVQQS VGVSIQNGLH IAHNRRISVN
GTASLHHGSK DSSNATVRVS AESSSPSIGS NHTAGDVSGQ SLNTAGNKTC VNCNSTFSPK
WWTVESSGDS RLLMNGVGQI DGSHAVPTTA SPYQTPSIMN GDIALTDADR MITSHQGSLP
CHPNPTRTLH ECHKCHVKKL SASPLESEAR PSPYTAKRDP SLPAARASEF PNNRYSPSPH
PHAHPTPQQP NLPIPPIVPI HGHGHSSTDW RPEYEQQSND YGPSLMLNGI PAGGPPSNGL
QSLGPRSFHG APPPPPPPPP PHLNGYHPSI QPHHQAPPPQ HYTNNVPPPP PPHTFSAHQS
PYSPVPLPPP HSPQPSRPYT TTTSPPASQF SPPHTLSSLP PPGPRMFSVE RSIAPSHPSP
SSTRRNLDPQ CPATPAAGDE NIAHSSGPGP APVRPSSSGR FHGVNGPVAG SGSGSGSGAS
ASPSLKNLLS
//
