ID C1H976_PARBA Unreviewed; 313 AA.
AC C1H976;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=PENR2 protein {ECO:0000313|EMBL:EEH36899.1};
GN ORFNames=PAAG_07317 {ECO:0000313|EMBL:EEH36899.1};
OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS brasiliensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502779 {ECO:0000313|EMBL:EEH36899.1, ECO:0000313|Proteomes:UP000002059};
RN [1] {ECO:0000313|EMBL:EEH36899.1, ECO:0000313|Proteomes:UP000002059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-826 / Pb01 {ECO:0000313|Proteomes:UP000002059};
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN294014; EEH36899.1; -; Genomic_DNA.
DR RefSeq; XP_002790780.1; XM_002790734.1.
DR AlphaFoldDB; C1H976; -.
DR STRING; 502779.C1H976; -.
DR GeneID; 9094036; -.
DR KEGG; pbl:PAAG_07317; -.
DR VEuPathDB; FungiDB:PAAG_07317; -.
DR eggNOG; KOG1318; Eukaryota.
DR HOGENOM; CLU_046871_3_0_1; -.
DR OMA; KMVPGCE; -.
DR OrthoDB; 1475275at2759; -.
DR Proteomes; UP000002059; Partially assembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd11398; bHLHzip_scCBP1; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR047206; bHLHzip_scCBP1-like.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR47787; CENTROMERE-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR47787:SF1; CENTROMERE-BINDING PROTEIN 1; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002059}.
FT DOMAIN 174..222
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 313 AA; 34025 MW; 50FDCA82166EEED8 CRC64;
MSDQQLPSTD ASTGSNKRKR EMMDAGDGQR LTRSSHGQNS NGNLQGAYHP FDHGLPNTTE
LSQIDQQLLQ HVGNQNGVSV SVADDNAMTA KAALAAHGSE SKYPPPGPSF ESNAAALAHG
LTFGHDDVNV NVAQVPMGNV NVHGHSTAAA VYAAREAQNI NPKPTVGSAE WHTIRKNNHK
EVERRRRETI NEGINEIAKM VPGCEKAKGS ILQRAIHYIS KLQEETKDMA ARWDTANMTT
NHALAEIGAQ NTKLKEEVNR RGEVAAKWMM RCKEAGLEFE DYEIDEKGLG MVEVDDGQGE
AGQGQQVQQQ EAV
//
