ID C1MIX8_MICPC Unreviewed; 664 AA.
AC C1MIX8;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Divalent Anion:Na+ symporter family {ECO:0000313|EMBL:EEH60992.1};
GN ORFNames=MICPUCDRAFT_31122 {ECO:0000313|EMBL:EEH60992.1};
OS Micromonas pusilla (strain CCMP1545) (Picoplanktonic green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=564608 {ECO:0000313|Proteomes:UP000001876};
RN [1] {ECO:0000313|EMBL:EEH60992.1, ECO:0000313|Proteomes:UP000001876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1545 {ECO:0000313|EMBL:EEH60992.1,
RC ECO:0000313|Proteomes:UP000001876};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GG663735; EEH60992.1; -; Genomic_DNA.
DR RefSeq; XP_003055740.1; XM_003055694.1.
DR AlphaFoldDB; C1MIX8; -.
DR STRING; 564608.C1MIX8; -.
DR GeneID; 9680276; -.
DR KEGG; mpp:MICPUCDRAFT_31122; -.
DR eggNOG; KOG2639; Eukaryota.
DR OMA; SVGMAEF; -.
DR OrthoDB; 276814at2759; -.
DR Proteomes; UP000001876; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR43652; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR PANTHER; PTHR43652:SF2; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001876};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 540..562
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 582..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 209..296
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 303..387
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT REGION 633..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 633..647
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 664 AA; 69879 MW; 0A4D25A04613A89A CRC64;
MGEQWEGWYC VSIMFITFVA LLKNVAGPDI LMLGALAMML AAGTVDIDSG LAGFSNKGLL
TVACLFVVAA GISHTGALDY YMGRLLGHPK DAASAQIRLM VPIAFVSAFL NNTPVVAIMI
PILQKWAHKI GVHKAQLFIP LSFASILGGT CTLIGTSTNL VVEGMMRDRY PEEEPMGLFA
LSIYGVPVAM SGMAYILIAA PRTKPRRRRW NADLRAMTDF TCPVRVLPEG ALDGKTLMNA
GLRGLAGLFL TAVQVAGSES EAMAVPGPEY VLQGGDVLWF AGDANGVHQL FRIPGLVPQT
KQVDKLNINK TDRRLVQAVI AVRSPLCGQT VRDSHFRTCY DAVIIAVQRS GGRIQAKIGD
IVLSAGDVLL LDTGGSFLRL YKHDPAFALV SEVENSSPPQ FEKLLPACLT AVVMIVVFVA
GLLDLFVAAL LASGVMLATG CLTQKQAREA VKWDIIVTIA AAFGISAAME QSGVASAIAD
TLVDGGNAAG TGNAGILVAI YAATVFMCNV VGNNAAAALM YPIAAGAAEQ QGIERDQMSF
LLMLAASASF MSPFGYQTNL MVYGPGGYVF ADFLRFGSPM QVVQMVVSVT VVLLGGLWWT
AWVGGFGMIL LIYGGRSVAA ALEAALCGGD ASKEKDEGEE DYGDGALKSV PESEASAGPL
AGVV
//
