ID C1MKR5_MICPC Unreviewed; 458 AA.
AC C1MKR5;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Plastidial delta 12 fatty acid desaturase {ECO:0000313|EMBL:EEH59807.1};
GN Name=FAD6 {ECO:0000313|EMBL:EEH59807.1};
GN ORFNames=MICPUCDRAFT_70877 {ECO:0000313|EMBL:EEH59807.1};
OS Micromonas pusilla (strain CCMP1545) (Picoplanktonic green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=564608 {ECO:0000313|Proteomes:UP000001876};
RN [1] {ECO:0000313|EMBL:EEH59807.1, ECO:0000313|Proteomes:UP000001876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1545 {ECO:0000313|EMBL:EEH59807.1,
RC ECO:0000313|Proteomes:UP000001876};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
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DR EMBL; GG663736; EEH59807.1; -; Genomic_DNA.
DR RefSeq; XP_003056431.1; XM_003056385.1.
DR AlphaFoldDB; C1MKR5; -.
DR STRING; 564608.C1MKR5; -.
DR GeneID; 9681525; -.
DR KEGG; mpp:MICPUCDRAFT_70877; -.
DR eggNOG; ENOG502QQNB; Eukaryota.
DR OMA; FYLFHNY; -.
DR OrthoDB; 4215at2759; -.
DR BRENDA; 1.14.19.3; 13579.
DR Proteomes; UP000001876; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF76; MICROSOMAL OMEGA-6 FATTY ACID DESATURASE; 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001876};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 108..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 136..409
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 458 AA; 50660 MW; 0B0CA6C71755019F CRC64;
MYGFDHAYSP VSKLAPLSRL SSNVRCARFY RASTAHRLGP DRRSARGLRA RQPSTITAAA
VSFDDIPRSG LNGKALMFPP KKDFPTRAEV LSSIPEDCFK KDTGKSMFYA AISTLMTFGC
GVLGYLYIPL SLNFWPVWLA YAAVTGTIAT GCWVVAHECG HNAFSDNRFI QDLVGYTLHS
LLLVPYFSWQ RSHAVHHSRT NHLTEGETHV PYIKGERKGT LNLNLHDSIG EGPFAFVQLF
AHLIFGWPAY LLTGATGGSA RGITNHFLPM INSGPVELFP GSWKNKVWWS DVGVAGVCVV
LASLLSQVGL STVAALYFGP YMFVNVWLVL YTWLQHTDTD VPHLASSEWS YIKGAFLTID
RPYGALFDFL HHRIGSTHVA HHVECAIPHY NALKATDSLK AQFPSLYLYD STPIASALWR
VASKCVAVEQ RDTGRDILWT FSDKKSPLHS TAASNSIA
//
