ID C1MLY6_MICPC Unreviewed; 81 AA.
AC C1MLY6;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 03-MAY-2023, entry version 43.
DE RecName: Full=sulfiredoxin {ECO:0000256|ARBA:ARBA00013055};
DE EC=1.8.98.2 {ECO:0000256|ARBA:ARBA00013055};
DE Flags: Fragment;
GN ORFNames=MICPUCDRAFT_9111 {ECO:0000313|EMBL:EEH58947.1};
OS Micromonas pusilla (strain CCMP1545) (Picoplanktonic green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=564608 {ECO:0000313|Proteomes:UP000001876};
RN [1] {ECO:0000313|EMBL:EEH58947.1, ECO:0000313|Proteomes:UP000001876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1545 {ECO:0000313|EMBL:EEH58947.1,
RC ECO:0000313|Proteomes:UP000001876};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-dithiol + ATP + S-hydroxy-S-oxy-L-cysteinyl-
CC [peroxiredoxin] = [protein]-disulfide + ADP + phosphate + S-hydroxy-
CC L-cysteinyl-[peroxiredoxin]; Xref=Rhea:RHEA:17545, Rhea:RHEA-
CC COMP:10593, Rhea:RHEA-COMP:10594, Rhea:RHEA-COMP:13681, Rhea:RHEA-
CC COMP:17976, ChEBI:CHEBI:29950, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:50058, ChEBI:CHEBI:61973, ChEBI:CHEBI:61974,
CC ChEBI:CHEBI:456216; EC=1.8.98.2;
CC Evidence={ECO:0000256|ARBA:ARBA00034024};
CC -!- SIMILARITY: Belongs to the sulfiredoxin family.
CC {ECO:0000256|ARBA:ARBA00009609}.
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DR EMBL; GG663737; EEH58947.1; -; Genomic_DNA.
DR RefSeq; XP_003057302.1; XM_003057256.1.
DR AlphaFoldDB; C1MLY6; -.
DR STRING; 564608.C1MLY6; -.
DR GeneID; 9682284; -.
DR KEGG; mpp:MICPUCDRAFT_9111; -.
DR eggNOG; KOG3388; Eukaryota.
DR OMA; TIKCKIR; -.
DR OrthoDB; 5482730at2759; -.
DR Proteomes; UP000001876; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0032542; F:sulfiredoxin activity; IEA:UniProtKB-EC.
DR CDD; cd16395; Srx; 1.
DR Gene3D; 3.90.1530.10; Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain; 1.
DR InterPro; IPR003115; ParB/Sulfiredoxin_dom.
DR InterPro; IPR036086; ParB/Sulfiredoxin_sf.
DR InterPro; IPR016692; Sulfiredoxin.
DR PANTHER; PTHR21348:SF2; SULFIREDOXIN-1; 1.
DR PANTHER; PTHR21348; UNCHARACTERIZED; 1.
DR Pfam; PF02195; ParBc; 1.
DR PIRSF; PIRSF017267; Sulfiredoxin; 1.
DR SMART; SM00470; ParB; 1.
DR SUPFAM; SSF110849; ParB/Sulfiredoxin; 1.
PE 3: Inferred from homology;
KW Antioxidant {ECO:0000256|ARBA:ARBA00022862};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRSR:PIRSR017267-
KW 1};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR017267-2};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRSR:PIRSR017267-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001876}.
FT DOMAIN 1..80
FT /note="ParB/Sulfiredoxin"
FT /evidence="ECO:0000259|SMART:SM00470"
FT BINDING 49..52
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR017267-1"
FT DISULFID 50
FT /note="Interchain"
FT /evidence="ECO:0000256|PIRSR:PIRSR017267-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEH58947.1"
FT NON_TER 81
FT /evidence="ECO:0000313|EMBL:EEH58947.1"
SQ SEQUENCE 81 AA; 9281 MW; 26E6A9F4A0719D67 CRC64;
IDQIARPLGK TRANDQEKVK WLMESIADVG LQEPIDVLEV DGKYYGFSGC HRFEAHVKLG
RETIECRVLK ATRATLQMHL R
//
