ID C1MTG3_MICPC Unreviewed; 794 AA.
AC C1MTG3;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Predicted protein {ECO:0000313|EMBL:EEH57313.1};
GN ORFNames=MICPUCDRAFT_58059 {ECO:0000313|EMBL:EEH57313.1};
OS Micromonas pusilla (strain CCMP1545) (Picoplanktonic green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=564608 {ECO:0000313|Proteomes:UP000001876};
RN [1] {ECO:0000313|EMBL:EEH57313.1, ECO:0000313|Proteomes:UP000001876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1545 {ECO:0000313|EMBL:EEH57313.1,
RC ECO:0000313|Proteomes:UP000001876};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
CC -!- SIMILARITY: Belongs to the peptidase C2 family.
CC {ECO:0000256|ARBA:ARBA00007623}.
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DR EMBL; GG663739; EEH57313.1; -; Genomic_DNA.
DR RefSeq; XP_003058858.1; XM_003058812.1.
DR AlphaFoldDB; C1MTG3; -.
DR STRING; 564608.C1MTG3; -.
DR GeneID; 9684297; -.
DR KEGG; mpp:MICPUCDRAFT_58059; -.
DR eggNOG; KOG0045; Eukaryota.
DR OMA; FKFARRT; -.
DR OrthoDB; 1833386at2759; -.
DR Proteomes; UP000001876; Unassembled WGS sequence.
DR GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd14345; UBA_UBXD7; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR022684; Calpain_cysteine_protease.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR001300; Peptidase_C2_calpain_cat.
DR InterPro; IPR010666; Znf_GRF.
DR PANTHER; PTHR10183; CALPAIN; 1.
DR PANTHER; PTHR10183:SF379; CALPAIN-A-RELATED; 1.
DR Pfam; PF00648; Peptidase_C2; 2.
DR Pfam; PF14555; UBA_4; 1.
DR Pfam; PF06839; zf-GRF; 1.
DR PRINTS; PR00704; CALPAIN.
DR SMART; SM00230; CysPc; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS50203; CALPAIN_CAT; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS51999; ZF_GRF; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protease {ECO:0000256|PROSITE-ProRule:PRU00239};
KW Reference proteome {ECO:0000313|Proteomes:UP000001876};
KW Thiol protease {ECO:0000256|PROSITE-ProRule:PRU00239};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01343}.
FT DOMAIN 186..237
FT /note="GRF-type"
FT /evidence="ECO:0000259|PROSITE:PS51999"
FT DOMAIN 260..619
FT /note="Calpain catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50203"
FT REGION 81..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 271
FT /evidence="ECO:0000256|PIRSR:PIRSR622684-1,
FT ECO:0000256|PROSITE-ProRule:PRU00239"
FT ACT_SITE 495
FT /evidence="ECO:0000256|PIRSR:PIRSR622684-1,
FT ECO:0000256|PROSITE-ProRule:PRU00239"
FT ACT_SITE 563
FT /evidence="ECO:0000256|PIRSR:PIRSR622684-1,
FT ECO:0000256|PROSITE-ProRule:PRU00239"
SQ SEQUENCE 794 AA; 83965 MW; 2BA22728D7FE10BB CRC64;
MPPRAKRKAP PPVAEVRDAD VEAFVAVTGA DDARARRALL ACGGELQRAV DRHFAVVAPA
PAPAPAPAAA PLGQTSLHDA AKTREKTETT TPREAPPRFD LDVSTIPTAP SRDADGWVTT
PSQEDEAEAE TRDATIEWAT RCVRAPRFDD GSFPPDASSI DGRRKGRGKG GKGGEHDEAV
VVPRWCACDP PRRARVKRAQ RDGPNQGREY YACGLAAARG VFPPPKPCEF FAWADDAPSK
KSSVETEWRR LTGADGVFDP AHVRQGAVGD CWLLSALAVI AERQDLARRV VGPSAASPAA
AAAAAASGAY LVRLFLGGRW RGVVVDPCLP VAGRSVEVSR GANGPRPEVN KRRALDDFAP
AFSRASGNRL WVPVVEKAYA KAHGSYHAIS GGYISEGLLD LTGCPTETIA LLGAGSEHYG
GETASHTTPF AWCTPFLKDF SRRHSSPALP FQRLTGGGGA FDEARAWEKV LSYCEAGFPM
GCATSSGGRG LVGGHAYSVL DVRQLHGVAV GRQTKLDGFV EREVEIVDPA PALVSASASK
YASSAAAADA SSPPPLRLVR VRNPWGRKEW NGEWGAKSET WTSRLGAELG NTRADDGTFW
MSWHDFLAAF SVVDVCKAHR GWHALSLPGA AHRAEGDGPP GTTRAAVDFG MISSEDGDAF
EIEVAGDGEG GGGGGGGGSW AYVMALQHTK RGRGGEAFWY ADVGIAVYEK NARANAAAAD
DAWTPLGAVL GAKERVAQAE LMLERGKRYL ARLFSVGGGA AGPPTAPVTL RVYRRVLSVH
WSPYDRVGAV NADP
//
