ID C1MYC6_MICPC Unreviewed; 752 AA.
AC C1MYC6;
DT 26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT 26-MAY-2009, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Guanylate cyclase {ECO:0000313|EMBL:EEH55321.1};
GN Name=GCY {ECO:0000313|EMBL:EEH55321.1};
GN ORFNames=MICPUCDRAFT_59862 {ECO:0000313|EMBL:EEH55321.1};
OS Micromonas pusilla (strain CCMP1545) (Picoplanktonic green alga).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Mamiellaceae; Micromonas.
OX NCBI_TaxID=564608 {ECO:0000313|Proteomes:UP000001876};
RN [1] {ECO:0000313|EMBL:EEH55321.1, ECO:0000313|Proteomes:UP000001876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1545 {ECO:0000313|EMBL:EEH55321.1,
RC ECO:0000313|Proteomes:UP000001876};
RX PubMed=19359590; DOI=10.1126/science.1167222;
RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L.,
RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E.,
RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M.,
RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H.,
RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., Gready J.E.,
RA John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., Moreau H.,
RA Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., Piegu B.,
RA Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., Zelensky A.,
RA Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., Van de Peer Y.,
RA Grigoriev I.V.;
RT "Green evolution and dynamic adaptations revealed by genomes of the marine
RT picoeukaryotes Micromonas.";
RL Science 324:268-272(2009).
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DR EMBL; GG663742; EEH55321.1; -; Genomic_DNA.
DR RefSeq; XP_003060552.1; XM_003060506.1.
DR AlphaFoldDB; C1MYC6; -.
DR STRING; 564608.C1MYC6; -.
DR GeneID; 9685715; -.
DR KEGG; mpp:MICPUCDRAFT_59862; -.
DR eggNOG; KOG1023; Eukaryota.
DR OMA; CAIMPPP; -.
DR OrthoDB; 2898719at2759; -.
DR Proteomes; UP000001876; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR11920:SF335; GUANYLATE CYCLASE 32E; 1.
DR PANTHER; PTHR11920; GUANYLYL CYCLASE; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001876};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 464..599
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REGION 277..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 694..725
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 752 AA; 81478 MW; 6478CEF66C3D5B18 CRC64;
MPSRGRRGRA SRGGDEYVGD AFLLQASVVL CAAAAVGWTV LQIALYGGTE PALIVIPLLY
IAGVAAAIAY ERFWLKRRPF DTVAFAHLSG MLLLPALLQM EYGGFQRSGG VLAWSSVSPF
TAMLLYNDNV RVQAVTFAGF VFMCAACFLH ESLNRAYGED GAAIAGDHVV KVWLWQIYVY
AIATVIGVTL NACVLMHLCI SKSTNAIEAH KALACAIMPP PVAKEVFEVQ WKRLKEGKKM
QKQESRTWKN APASGAKKKN VFARVINAIV AITFGSSGSG SGGGSSASES RSRSRQSSKR
SGMGLSSIGG GGGGARSDDF CDDSTHGGRA PSERSEGDLD SDTASASDGN SMRGDDAYLR
AIQTTQALRA PSEDTIALRD RDLDVFFEGA PDDAGADAAG EDVSSQNQIE KPRRRSSILY
GKPGVSGGGG GDGDGAAANS LRRQSTFRKR RGASVKAREH KDVTVIFCDI VGFSAMCKVV
KPYRVLRFLE TYFQMLDDVA EEHGVTKVRT VGDGYLAVSG LMAEMGVKED ARQHRLRALH
FAAGVLTYMK DERVYMPNGV EVKIRIGLAA GSVYSGVVGR TCMQFDIYGD VANLAARMEQ
TCRYDGVHFP RAMYDAMKGE LSEEQGRTFD ALKWEFRDGV EIKGMDAIDT VSLVRDGNEE
AIEMELMGGM SNDQQRAVTT HIGVLAEAFR QKSWTTTRKR SVDDERSEDG SENSKEDEPE
KPKKPPTQRQ VSFSVGNVPS LARPWELPPA ED
//
