ID   C2BFK4_9FIRM            Unreviewed;       327 AA.
AC   C2BFK4;
DT   16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Signal peptide peptidase SppA, 36K type {ECO:0000313|EMBL:EEI86291.1};
DE            EC=3.4.-.- {ECO:0000313|EMBL:EEI86291.1};
GN   Name=sppA {ECO:0000313|EMBL:EEI86291.1};
GN   ORFNames=HMPREF0072_1124 {ECO:0000313|EMBL:EEI86291.1};
OS   Anaerococcus lactolyticus ATCC 51172.
OC   Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC   Anaerococcus.
OX   NCBI_TaxID=525254 {ECO:0000313|EMBL:EEI86291.1, ECO:0000313|Proteomes:UP000005984};
RN   [1] {ECO:0000313|EMBL:EEI86291.1, ECO:0000313|Proteomes:UP000005984}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51172 {ECO:0000313|EMBL:EEI86291.1,
RC   ECO:0000313|Proteomes:UP000005984};
RA   Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA   Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA   Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA   Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA   Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA   Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA   Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA   Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA   Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA   Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S49 family.
CC       {ECO:0000256|ARBA:ARBA00008683}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEI86291.1}.
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DR   EMBL; ABYO01000196; EEI86291.1; -; Genomic_DNA.
DR   AlphaFoldDB; C2BFK4; -.
DR   STRING; 525254.HMPREF0072_1124; -.
DR   eggNOG; COG0616; Bacteria.
DR   HOGENOM; CLU_046540_0_1_9; -.
DR   Proteomes; UP000005984; Unassembled WGS sequence.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd07023; S49_Sppa_N_C; 1.
DR   Gene3D; 6.20.330.10; -; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR004635; Pept_S49_SppA.
DR   InterPro; IPR002142; Peptidase_S49.
DR   InterPro; IPR047272; S49_SppA_C.
DR   NCBIfam; TIGR00706; SppA_dom; 1.
DR   PANTHER; PTHR42987; PEPTIDASE S49; 1.
DR   PANTHER; PTHR42987:SF4; PROTEASE SLR0021-RELATED; 1.
DR   Pfam; PF01343; Peptidase_S49; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:EEI86291.1};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005984}.
FT   DOMAIN          121..271
FT                   /note="Peptidase S49"
FT                   /evidence="ECO:0000259|Pfam:PF01343"
SQ   SEQUENCE   327 AA;  35886 MW;  3977784720954D72 CRC64;
     MKNNAKRWIA VGLAVLVLVA SMFMKDASEE KEAKGLAYLR DWGKSTLFDQ EVIQGTNSAE
     KIRKISLEGV IQGDENSEFV ISELKDAAKD PTTKGVILTV NSPGGSVYVS EKIAKEIKSL
     KAKKIPVYSV MEEMAASGGY YISAPTDRIY ASNETLTGSI GVIMGGRSFQ GLFEKYGIKE
     QNVVSGKMKD TGTMGRDLNA EEKAYLQALV DSAFGRFVKI VSEGRHMSEK DVRKLADGRV
     YDGAQAVKNG LVDKIGDIDM AIADMIKENK LNDPQVVESS YANISLRQLF QKVSDLKKSS
     SDLAILKELM EENRQAPMYI YGGVYGR
//