ID   C2EUZ7_9LACO            Unreviewed;       775 AA.
AC   C2EUZ7;
DT   16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 1.
DT   27-MAR-2024, entry version 72.
DE   RecName: Full=UvrD-like helicase ATP-binding domain-containing protein {ECO:0000259|PROSITE:PS51198};
GN   ORFNames=HMPREF0549_1283 {ECO:0000313|EMBL:EEJ40277.1};
OS   Limosilactobacillus vaginalis DSM 5837 = ATCC 49540.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Limosilactobacillus.
OX   NCBI_TaxID=1423814 {ECO:0000313|EMBL:EEJ40277.1, ECO:0000313|Proteomes:UP000004483};
RN   [1] {ECO:0000313|EMBL:EEJ40277.1, ECO:0000313|Proteomes:UP000004483}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49540 {ECO:0000313|EMBL:EEJ40277.1,
RC   ECO:0000313|Proteomes:UP000004483};
RA   Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA   Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA   Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA   Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA   Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA   Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA   Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA   Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA   Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA   Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEJ40277.1}.
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DR   EMBL; ACGV01000140; EEJ40277.1; -; Genomic_DNA.
DR   AlphaFoldDB; C2EUZ7; -.
DR   STRING; 1423814.HMPREF0549_1283; -.
DR   eggNOG; COG3973; Bacteria.
DR   HOGENOM; CLU_010312_4_1_9; -.
DR   Proteomes; UP000004483; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.160; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR048228; HelD_bacillota.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   NCBIfam; NF041464; HelD_BACSU; 1.
DR   PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          214..606
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   COILED          16..50
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   BINDING         235..242
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   775 AA;  89502 MW;  B6CBBCE1ADF1071F CRC64;
     MEVERVTEQS VQEFEQQHLD HVIDEIKQAK EKAEEKIHTA RHDIKGINKQ IDDIHLNTTT
     YSGMMDTAMS FRAQQQMLDE RQNSWQHAAD RLSTLKRLEK KPYFARIDFQ EKGAEKPETV
     YIGLASFSDQ PDHFLVYDWR APISSIYYEG KLGKVSYETP VGTQEVNMTL KRQFQIDDGT
     IVTIFDTDEQ VGDQMLLEAL GTHSSTKMKS IVTTIQRTQN EIIRDTKDDL LFVQGAAGSG
     KTAAVLQRVA WLLYRYRGNL SSSQVVLFSP NQLFNDYIDQ VLPELGEHNM VQMTYYQFAN
     RRVPRLHVET LAQRFDSSQD PTTKKAVQLT TSLAYFKATG RYAKHLGKAN MRFRNLMFRG
     KVFISKEKIK EIYYSFNNNY NLGNRLDGTK EALIKYLNHR VSVEMRSKWA EEAVQNLSKE
     QIDDLMDNQP REFADENQQF KFLARQIVMK ALTPVKRAID HNLWLNINAQ FIHLLRATPK
     LIDLDKFGIS TTEWEAYVEK TKDDLRQGNI SANGITIYLY LYDLMTGKKG QRDIRYVFID
     EVQDYDAYQL AYLKFRFPNA RFTLLGDLNQ AIFTHENSRS LLRQLGTMFD PEKTKVVQLT
     KSYRSTKQIT DFTKHFLTNG EAIEAFDRNG DLPTVIETDS YSTGVDSVVE TLKKYQQEHD
     AVAIIGKTLN DCEKLYDELK RRNVKTTLIR TENQRLVDGV IIVPSFLAKG LEFDAVIAWN
     VNEQEYPDDS ERQLLYTIAS RAMHALTMIS VGKVTPLLKG VPDDLYSLVK RGKNN
//