ID IHFA_PSEFS Reviewed; 100 AA.
AC C3JZN1;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE RecName: Full=Integration host factor subunit alpha {ECO:0000255|HAMAP-Rule:MF_00380};
DE Short=IHF-alpha {ECO:0000255|HAMAP-Rule:MF_00380};
GN Name=ihfA {ECO:0000255|HAMAP-Rule:MF_00380};
GN Synonyms=himA {ECO:0000255|HAMAP-Rule:MF_00380};
GN OrderedLocusNames=PFLU_4142;
OS Pseudomonas fluorescens (strain SBW25).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=216595;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SBW25;
RX PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA Jackson R.W., Preston G.M., Zhang X.-X., Moon C.D., Gehrig S.M.,
RA Godfrey S.A.C., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT "Genomic and genetic analyses of diversity and plant interactions of
RT Pseudomonas fluorescens.";
RL Genome Biol. 10:R51.1-R51.16(2009).
CC -!- FUNCTION: This protein is one of the two subunits of integration host
CC factor, a specific DNA-binding protein that functions in genetic
CC recombination as well as in transcriptional and translational control.
CC {ECO:0000255|HAMAP-Rule:MF_00380}.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000255|HAMAP-
CC Rule:MF_00380}.
CC -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC {ECO:0000255|HAMAP-Rule:MF_00380}.
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DR EMBL; AM181176; CAY50633.1; -; Genomic_DNA.
DR RefSeq; WP_002553164.1; NC_012660.1.
DR AlphaFoldDB; C3JZN1; -.
DR SMR; C3JZN1; -.
DR STRING; 294.SRM1_02095; -.
DR GeneID; 78552156; -.
DR eggNOG; COG0776; Bacteria.
DR HOGENOM; CLU_105066_1_3_6; -.
DR OrthoDB; 9797747at2; -.
DR Proteomes; UP000002332; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR CDD; cd13835; IHF_A; 1.
DR Gene3D; 4.10.520.10; IHF-like DNA-binding proteins; 1.
DR HAMAP; MF_00380; IHF_alpha; 1.
DR InterPro; IPR000119; Hist_DNA-bd.
DR InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR InterPro; IPR005684; IHF_alpha.
DR NCBIfam; TIGR00987; himA; 1.
DR PANTHER; PTHR33175; DNA-BINDING PROTEIN HU; 1.
DR PANTHER; PTHR33175:SF2; INTEGRATION HOST FACTOR SUBUNIT ALPHA; 1.
DR Pfam; PF00216; Bac_DNA_binding; 1.
DR PRINTS; PR01727; DNABINDINGHU.
DR SMART; SM00411; BHL; 1.
DR SUPFAM; SSF47729; IHF-like DNA-binding proteins; 1.
DR PROSITE; PS00045; HISTONE_LIKE; 1.
PE 3: Inferred from homology;
KW DNA recombination; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation; Translation regulation.
FT CHAIN 1..100
FT /note="Integration host factor subunit alpha"
FT /id="PRO_1000205692"
FT REGION 54..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 100 AA; 11476 MW; 6EEE655D1653A50F CRC64;
MGALTKAEMA ERLYEELGLN KREAKELVEL FFEEIRHALE DNEQVKLSGF GNFDLRDKRQ
RPGRNPKTGE EIPITARRVV TFRPGQKLKA RVEAYAGTKS
//
