ID C3K190_PSEFS Unreviewed; 1019 AA.
AC C3K190;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=AcrB/AcrD/AcrF RND family transmembrane transporter {ECO:0000313|EMBL:CAI2799127.1, ECO:0000313|EMBL:CAY51923.1};
GN OrderedLocusNames=PFLU_4977 {ECO:0000313|EMBL:CAY51923.1};
OS Pseudomonas fluorescens (strain SBW25).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=216595 {ECO:0000313|EMBL:CAY51923.1};
RN [1] {ECO:0000313|EMBL:CAY51923.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SBW25 {ECO:0000313|EMBL:CAY51923.1};
RX PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA Jackson R.W., Preston G.M., Zhang X.X., Moon C.D., Gehrig S.M.,
RA Godfrey S.A., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT "Genomic and genetic analyses of diversity and plant interactions of
RT Pseudomonas fluorescens.";
RL Genome Biol. 10:R51.1-R51.16(2009).
RN [2] {ECO:0000313|EMBL:CAI2799127.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SBW25 {ECO:0000313|EMBL:CAI2799127.1};
RA Fortmann-Grote C.;
RL Submitted (OCT-2023) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; OV986001; CAI2799127.1; -; Genomic_DNA.
DR EMBL; AM181176; CAY51923.1; -; Genomic_DNA.
DR RefSeq; WP_015885670.1; NC_012660.1.
DR AlphaFoldDB; C3K190; -.
DR PATRIC; fig|216595.4.peg.5112; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_6; -.
DR OrthoDB; 9757904at2; -.
DR Proteomes; UP001152918; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF14; BLL4319 PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 333..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 846..866
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 873..893
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 899..923
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 944..965
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 977..1003
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1019 AA; 110872 MW; EF60D306B7A9FF9F CRC64;
MTITDLFIRR PVLALVVSLL IVLLGWQAYG KLPLRQFPQM ESALITVTTV SPGSSAESVQ
SYITQPLQKS LASAQGIDYM KSSSRQNISI ISIYGRVGAD SDRLFTELLA KTNEVRNQLP
REIDDPILSK VAADNTALMY LSFSSEIMNN AQITDYLSRV IQPRLVTLPG MAEAQIIGNQ
SFAMRLWLDP IKLAGFGLSA SEVTQAIKRY NVQPTAGDVT GEYVVTSIQT NTELHSVEGF
NAIPLKTKGD SQVRLGDVAR VELGSQNYDS FSTFNGIPAL YISIKPAPDA NPLELAKHVR
ELLPQLQSQI PPGLDVDIAY DSTLYINASI DQVLSSLVEA IVIVVLVVFL FLGSLRSAVI
PVVTIPLSLI GTLFFMQVMG YSINVLTLLA MVLAIGLVVD DAIVVMENIH RHIERGKSPL
EAAIRGAREI CVPVLSMTIT LAAVYTPIGF LQGLTGALFK EFALTLAGAV VISGIVALTL
SPMMCAVLLR PEEQPKGLFL ILDRFFNALR KSYQQRLHQI MKAQSVVLVF ALVVLGLIPV
MLIFTLSELA PDEDKGLIFI LSSAPQPTNL AYLNTYTQAF IEPFKTLPEY QASFQINGLD
GVHSGVGGFL LKPWNERDRT QMQVLAPLRE KLDRIPGLQV FAFNLPSLPG GGEGLPFGFV
LSSQQDYESM MSVAERIKQR AIDSGKFAYV DIDLAFDRPE VVIDIDRTKA AQMGVSMEEL
SLTLATLLAE TEINRFSIDG HLYKVIAQVE RTYRDNPQWL SHYAVKNADG QLLPLSTLIK
VSSQQVRPRQ LNQFQQLNSV IVSGFPIVGM SHALETLQAI AQEEAPPGYT FDYSNATRQF
VQEGNALWGT FGLALAIIGL VLAAQFESLR DSLVILVTVP LSIAGALIAL FLGWSTLNIY
TQIGLVTLIG LISKHGILIV EFANQLRKEQ GLSPRAAVEE AAAIRLRPIL MTTLATVLGV
IPLILSSGAG AVSRFDIGLV IATGMSIGTL FTLFVLPSVY AALTKADPAA RTVGSTSSH
//
