ID C3K8U3_PSEFS Unreviewed; 207 AA.
AC C3K8U3;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Ubiquinone biosynthesis accessory factor UbiJ {ECO:0000256|HAMAP-Rule:MF_02215};
GN Name=ubiJ {ECO:0000256|HAMAP-Rule:MF_02215};
GN OrderedLocusNames=PFLU_0388 {ECO:0000313|EMBL:CAY46665.1};
OS Pseudomonas fluorescens (strain SBW25).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=216595 {ECO:0000313|EMBL:CAY46665.1};
RN [1] {ECO:0000313|EMBL:CAY46665.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SBW25 {ECO:0000313|EMBL:CAY46665.1};
RX PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA Jackson R.W., Preston G.M., Zhang X.X., Moon C.D., Gehrig S.M.,
RA Godfrey S.A., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT "Genomic and genetic analyses of diversity and plant interactions of
RT Pseudomonas fluorescens.";
RL Genome Biol. 10:R51.1-R51.16(2009).
RN [2] {ECO:0000313|EMBL:CAI2794712.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SBW25 {ECO:0000313|EMBL:CAI2794712.1};
RA Fortmann-Grote C.;
RL Submitted (OCT-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for ubiquinone (coenzyme Q) biosynthesis. Binds
CC hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain
CC and is essential for the stability of the Ubi complex. May constitute a
CC docking platform where Ubi enzymes assemble and access their SCP2-bound
CC polyprenyl substrates. {ECO:0000256|HAMAP-Rule:MF_02215}.
CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC {ECO:0000256|HAMAP-Rule:MF_02215}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02215}.
CC -!- SIMILARITY: Belongs to the UbiJ family. {ECO:0000256|HAMAP-
CC Rule:MF_02215}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; OV986001; CAI2794712.1; -; Genomic_DNA.
DR EMBL; AM181176; CAY46665.1; -; Genomic_DNA.
DR RefSeq; WP_012721798.1; NC_012660.1.
DR AlphaFoldDB; C3K8U3; -.
DR STRING; 294.SRM1_00437; -.
DR PATRIC; fig|216595.4.peg.623; -.
DR eggNOG; COG3165; Bacteria.
DR HOGENOM; CLU_100130_1_0_6; -.
DR OrthoDB; 9796077at2; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP001152918; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0032150; P:ubiquinone biosynthetic process from chorismate; IEA:InterPro.
DR HAMAP; MF_02215; UbiJ; 1.
DR InterPro; IPR003033; SCP2_sterol-bd_dom.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR InterPro; IPR038989; UbiJ.
DR PANTHER; PTHR38693:SF1; UBIQUINONE BIOSYNTHESIS ACCESSORY FACTOR UBIJ; 1.
DR PANTHER; PTHR38693; UBIQUINONE BIOSYNTHESIS PROTEIN UBIJ; 1.
DR Pfam; PF02036; SCP2; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_02215};
KW Ubiquinone {ECO:0000313|EMBL:CAI2794712.1};
KW Ubiquinone biosynthesis {ECO:0000256|HAMAP-Rule:MF_02215}.
FT DOMAIN 14..112
FT /note="SCP2"
FT /evidence="ECO:0000259|Pfam:PF02036"
FT COILED 173..200
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 207 AA; 23023 MW; 57FA8AE81322A543 CRC64;
MLLKGLLASV EHGLNRVLRL DSTALARLAH LNGKVIAVDC SSPALQLFIL PSDEGLLLAT
QWAAEADCTL RAPASSLLHL ALSRNKTAIL HGTEVHLEGD SSVLMDLAAV LQDLELDWEY
ELSRWIGPVA TQLISGHLRS RSRWYQQGFA SLNQNLAEYL SEESRTLVGE REAQARFREL
DKAKIDLERL EARFERLSRS LDPSDNA
//
