ID C3KCW1_PSEFS Unreviewed; 313 AA.
AC C3KCW1;
DT 16-JUN-2009, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:CAI2795709.1, ECO:0000313|EMBL:CAY47670.1};
GN OrderedLocusNames=PFLU_1417 {ECO:0000313|EMBL:CAY47670.1};
OS Pseudomonas fluorescens (strain SBW25).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=216595 {ECO:0000313|EMBL:CAY47670.1};
RN [1] {ECO:0000313|EMBL:CAY47670.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SBW25 {ECO:0000313|EMBL:CAY47670.1};
RX PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA Jackson R.W., Preston G.M., Zhang X.X., Moon C.D., Gehrig S.M.,
RA Godfrey S.A., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT "Genomic and genetic analyses of diversity and plant interactions of
RT Pseudomonas fluorescens.";
RL Genome Biol. 10:R51.1-R51.16(2009).
RN [2] {ECO:0000313|EMBL:CAI2795709.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SBW25 {ECO:0000313|EMBL:CAI2795709.1};
RA Fortmann-Grote C.;
RL Submitted (OCT-2023) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
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DR EMBL; OV986001; CAI2795709.1; -; Genomic_DNA.
DR EMBL; AM181176; CAY47670.1; -; Genomic_DNA.
DR RefSeq; WP_012722720.1; NC_012660.1.
DR AlphaFoldDB; C3KCW1; -.
DR PATRIC; fig|216595.4.peg.1647; -.
DR eggNOG; COG0119; Bacteria.
DR HOGENOM; CLU_022138_3_2_6; -.
DR OrthoDB; 9784013at2; -.
DR Proteomes; UP001152918; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:CAY47670.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 9..276
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 313 AA; 33730 MW; B8CB2EBC96F6644C CRC64;
MITDYSDPLI VQEVSPRDGL QIEPTWVETQ DKIALIDQLS LAGFSRIEAG SFVSPKAIPA
LRDGEQVFQG IERKPGVIYV ALIPNLKGAQ RAIESRADEL NLVMSASQTH NLANMRMRCE
ASLAAFGDIT RFAADHPVRL NGSIATTFGC PFEGKIDEDR VLQIVEAYQA LGITGISLAD
TTGMANPRQV ERLVKRVLQR VSARDLTLHF HNTRGLGLCN VLAAYEAGAR RFDAALGGLG
GCPFAPGASG NICTEDLVNL CEEVGIYTGI DLPHLLHMSR RLPALLGHEL PGQVAKAGRN
CDLHAPPAYI AAL
//
