ID   C3XRT4_BRAFL            Unreviewed;       493 AA.
AC   C3XRT4;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 65.
DE   RecName: Full=RmlD-like substrate binding domain-containing protein {ECO:0000259|Pfam:PF04321};
GN   ORFNames=BRAFLDRAFT_68401 {ECO:0000313|EMBL:EEN69402.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN69402.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN69402.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN69402.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
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DR   EMBL; GG666456; EEN69402.1; -; Genomic_DNA.
DR   RefSeq; XP_002613393.1; XM_002613347.1.
DR   AlphaFoldDB; C3XRT4; -.
DR   STRING; 7739.C3XRT4; -.
DR   eggNOG; KOG1430; Eukaryota.
DR   InParanoid; C3XRT4; -.
DR   GO; GO:0008830; F:dTDP-4-dehydrorhamnose 3,5-epimerase activity; IEA:InterPro.
DR   CDD; cd00438; cupin_RmlC; 1.
DR   CDD; cd05254; dTDP_HR_like_SDR_e; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR000888; RmlC-like.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   InterPro; IPR029903; RmlD-like-bd.
DR   PANTHER; PTHR43242; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR43242:SF1; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN; 1.
DR   Pfam; PF00908; dTDP_sugar_isom; 1.
DR   Pfam; PF04321; RmlD_sub_bind; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF51182; RmlC-like cupins; 1.
PE   4: Predicted;
FT   DOMAIN          188..484
FT                   /note="RmlD-like substrate binding"
FT                   /evidence="ECO:0000259|Pfam:PF04321"
SQ   SEQUENCE   493 AA;  54978 MW;  DE0889925FE7BA69 CRC64;
     MQGVERTPLA VRDAYLLEFA RHSDRRGHLE ELYNETRYPS GVTQHWAQVT CSTSYRNVLR
     GLHCSTYGKL VTCVAGRIYD VVVDLRKTSP TYLRWSAAIL SDNNRRQMYI PPNCGHGFYT
     LGDRNTVVYC QGGVYQPATE RDLLWFDPFV NVYWPLETSQ PPVLSDKDRS APCLDENEVQ
     VNPLRERYLI IGASGQVGGA LMEALLRHRS KEIVAIGTCN SNPREGMIPF CLEEAGRSED
     ACRDLLTMVR PSVVFICAAF TWTDGCEREP EKAQLVNCTA VVNLAQCAKV INSKVVFYST
     DYVFPGSDGD DTPGGGYSES CPCRPLQTYG ETKYRAEQKL LTVHPQALIL RTSTVFGPEE
     QGKNFVYQLV SNVTSGKDMA LTNVKCTPTY NRDLAAMTLK LIENGCSGIY HVIGDEAMAK
     MEFATRVARC LGIDTSKLRV TSDNDGGSRC KRPKDAILSS EKRKKDLPNF TCKNVEEAIT
     DWLEHSAGKS LMS
//