ID C3XW63_BRAFL Unreviewed; 1775 AA.
AC C3XW63;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=BRAFLDRAFT_117157 {ECO:0000313|EMBL:EEN67597.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN67597.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN67597.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN67597.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
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DR EMBL; GG666471; EEN67597.1; -; Genomic_DNA.
DR RefSeq; XP_002611587.1; XM_002611541.1.
DR STRING; 7739.C3XW63; -.
DR eggNOG; ENOG502QV6D; Eukaryota.
DR InParanoid; C3XW63; -.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR032770; DUF4537.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR46785; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B; 1.
DR PANTHER; PTHR46785:SF1; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B; 1.
DR Pfam; PF15057; DUF4537; 3.
DR Pfam; PF13768; VWA_3; 2.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
FT DOMAIN 510..686
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 711..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1048..1111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1262..1485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..751
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..780
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..806
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1055..1069
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1265..1291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1299..1328
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1329..1343
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1344..1369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1370..1389
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1390..1478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1775 AA; 201809 MW; 16A3AF24F6A3D5C5 CRC64;
MATTLDPVKI QAWREDPKFD LKHRDQPPRL DLYDFKTTVD MKVAIPTPPK STWELDVTPA
ISTQKWLTMY GLKKNKLTMG QILPAIGFKH SDDYDYSLKK PVSSRYGEGL FQRFPRKDGK
TFNVTVGKDK LKQIESRLMQ AITLYKRRLE WLTSESRRTF GVIEEHCVVL VLDIKTMDPA
EFEICRDIIR RVVNEQIANV AKFNLIRAQE DLSVWQPGGA IPYSAESRLS ALTWLEQIDR
MAGRSKTSTV ESVIRAMNDP NAEAVYLFYE GDLSNDTQHL LRQKLVGHRY PLHIVSFNAT
SEHTTRFLRD LTKLTGGRFH AFTLREGRTP IGGVPPGAGV RPEVIELFEE LEEARNTLAE
VQVLIQEAPD PKTQMATVKP RPKVKSEQYM GSKEWLENYG IDARRMDFYD VISGCCFKHS
DGVVELKKKP GDPHSQTDAD TKNKLINAKY CDRFAHTNWK DGSVVHVHVT PEFHRHYEQR
VSTVVQQVQR RIDWLREGSR ELFGTVIEEQ VYLLIDTSES MRDRLPFVKE KLFQLMQEQL
RHKAKFNIVK FDTRAIPWRD RLADVNEQNL ENAWQWVKGL TAGGTTNTLA AIRLALADHN
THAIYLLTDG RPDQLPKTIL AQVQLHPQVP IHTISFNCDD IEANRFLAQM SHDTNGRYHY
YSTDGRDPEG PEPFESEDIQ LLKQEIERAN SDLAKVAQLR DECAMLDWKN SGSKAIRNQR
PDSASTSSSK SHSRSSSGPT PPSTHRPSSA PSHRRPMTAL GFSHTTPSHT PRSTPRPRTA
NGYRSPAHAA HSHARHTPRR PRSRTSDLHK KPLFAGQTKT SLLRSMSAMS MTPRGFSTSG
NTWMLPETKE LFERQWVKYK ESLDEADRIL DKRKKKRKAI IPSHPLDMSS KKWLKKHGLV
AKKLTIMDAL APTAIPHKAK YVPILDKHVV SKVFDESLPI AHASSSGKLR LVNPQAVDLV
GYEERLQKAV DSYKKRLDMI VWRNLSQEER DQFDSEEAVS FLENRHAMMQ ALDRLGWPLP
QQDILLLEDE IARGQKYLRQ STDLRKAAEK LHQSTEEEDD DDDTASETSG VEAGDETERS
RTEFEGLGSV LEGSGGSAEK STPGSGKHRV KKVLDKLKGH KVIARKEEDG FYYPGIVVKC
PNSRHAIVDY HGNGRQLTPT RFVIPMGGAR ACPELRVGDF VLVKTTSEED LECWVPGIVQ
MTPRRREAQL KFYTILQFDK KRVTSLRKGI MKIPKSRYVF ACRYIKDAQQ INYEIPSVDI
VQRQATPDKA EDGERRPKSG RRGRHANNED SGHVETSSSE MSGEEEEKGD NTESETTKTS
RSTVHSRERL SDLGTSPSPH TTPHVSDEKI EEILSHQKTL EDLQRKLQEQ QEQQLEQQKA
IQQELQKLSE AVKNKPEPDP EPEPEAVDHK PPTEGDLENI EEENDQERVR EWLKKGEKEG
EEKEKDSSQK SEGKEEETEE KSKTKEPSEK EETKVSMHMD PQGNESVIIT QGDRGLLFSR
KPPEVVPEKA AVARHSLPKL GPGQEVLARW SDEGWYYRGT VKQALGDDSY YIEDSVGDME
RIFREDIITD EDDANNIIQS GDPVIGLHPS YSFSYAPGVV LEVLPDLWTV VRYYDGAEAK
VPREEVYKMA TEKFEKDVAY ILQCEDSWVG HAVVARDDND GAYHLGTVKE RVGNGRQYIV
QWANETMQVQ SSSCIFGAFT KRHALALGDR VLAVADPVAL IYLPGWITGT NGQKLVVKFC
NGTTSAHINP RQCFWLSQEY FDIAVSFWKT KQGAK
//
