ID   C3XWW2_BRAFL            Unreviewed;      1059 AA.
AC   C3XWW2;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=Death domain-containing protein {ECO:0000259|PROSITE:PS50017};
GN   ORFNames=BRAFLDRAFT_119651 {ECO:0000313|EMBL:EEN67222.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN67222.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN67222.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN67222.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
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DR   EMBL; GG666471; EEN67222.1; -; Genomic_DNA.
DR   RefSeq; XP_002611212.1; XM_002611166.1.
DR   AlphaFoldDB; C3XWW2; -.
DR   eggNOG; KOG4177; Eukaryota.
DR   InParanoid; C3XWW2; -.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd08779; Death_PIDD; 1.
DR   Gene3D; 2.60.220.30; -; 2.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR000488; Death_domain.
DR   PANTHER; PTHR28336; BA1-643; 1.
DR   PANTHER; PTHR28336:SF4; DEATH DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00531; Death; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   PROSITE; PS50017; DEATH_DOMAIN; 1.
PE   4: Predicted;
FT   DOMAIN          977..1049
FT                   /note="Death"
FT                   /evidence="ECO:0000259|PROSITE:PS50017"
FT   REGION          177..362
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          668..706
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        177..208
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        226..305
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        318..344
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1059 AA;  116769 MW;  3F8D2326BF6D8696 CRC64;
     MSATVGEEPA LQPRQVVAQV EALARQLERE NARIQAAGRA GCARGKVAGL LQELTEVLEE
     CARESGQLVA RIRHVRGVLS GTRDGLRLAG GRDRCAKGEA GVLKVSFGQG SGNNAFLISL
     IMDGQEHHGK DDTKEASVGD LRKSVDEAMT VAEKAEGTVA DVAREATAAI LEDAQELNHL
     ECIEDEPEKP EDMKATEEKD KEESVSESSN SNSDEVANNH SENILVDKPL ETEEKVADNE
     KESEKDKVKE VRPDEKSVQE TEKKDADKKD GDSKDNDSKE KTDNKSTLVE IDTKHSTEKK
     TATTSEDRPP ATTKTKTPST AEKKKSSRER EEINLNKPPE EDDDVDQIAP ANPGIWSTFP
     CDAQNDDGQS ELACLIKVDI QAVTSFPVTC QITNHLAPSA LAHNEELVSH VVQLSPAGLK
     LPVPAVVSLP YTWSRHVSRE LAVKKTTDGE NWKEVPLKGT DVVYKDRKGH FVEFQVSRLA
     CYVVVSRLKE ETFNLQKSKT KPNVFRSSVD QRIELNFPPG AIKTVGVLNV QVQPIDSVSL
     SALKSRCPDC DTLISTSPIV SLSLSPGLRL HKAVDITVPC PLNPAGNWAR DPTRPGTAGL
     SGLHKPVDIT VPCPLNPAGN WARDPTRPGT AGLGGSRKLG RSFPLVSGCR SVSGDTFLHR
     TLHDKTVFDS GEHFSPPLTR SRKLGGSSPR PGSAPAGRTS TMEEGDNGDD FLHLLGQAEG
     EESWAEVMGV RFRQNKKGLV TFEMSELLGK FIVLRTADPA AEQFQSLTET LPRMLETSLT
     LTDARLLLRT KTGDPERAVV RCVPARDVRE AEMQLDAAGY EEAEPSKEVL LKDGDQLVLK
     FSGNVARDTD GDSRDSVRLT FYSQRRTQAH FYIKEVNEFG NYSSPCYRGM VRFYGTRRHV
     GRPGGEDADR GPPDVIKNAF LGDTVEDGLD SICKLPVTLP KRERDPPRPP SAYRKLIESQ
     GPLVNDWLQW LASELDEDWD LLGHHLRVKR SRLQHIKRNN PDDMQQQAFD MLYSWRKSLP
     AATDKIGKLC RALSRVGRRD LAEELRERYS DHRKKNGKA
//