ID   C3XX79_BRAFL            Unreviewed;       660 AA.
AC   C3XX79;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   RecName: Full=Histidine kinase/HSP90-like ATPase domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=BRAFLDRAFT_210913 {ECO:0000313|EMBL:EEN67339.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN67339.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN67339.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN67339.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 90 family.
CC       {ECO:0000256|ARBA:ARBA00008239}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GG666471; EEN67339.1; -; Genomic_DNA.
DR   RefSeq; XP_002611329.1; XM_002611283.1.
DR   AlphaFoldDB; C3XX79; -.
DR   STRING; 7739.C3XX79; -.
DR   eggNOG; KOG0019; Eukaryota.
DR   InParanoid; C3XX79; -.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0019901; F:protein kinase binding; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   CDD; cd16927; HATPase_Hsp90-like; 1.
DR   Gene3D; 3.30.230.80; -; 1.
DR   Gene3D; 3.40.50.11260; -; 1.
DR   Gene3D; 1.20.120.790; Heat shock protein 90, C-terminal domain; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   HAMAP; MF_00505; HSP90; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR037196; HSP90_C.
DR   InterPro; IPR001404; Hsp90_fam.
DR   InterPro; IPR020575; Hsp90_N.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   PANTHER; PTHR11528:SF44; HEAT SHOCK PROTEIN 75 KDA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11528; HEAT SHOCK PROTEIN 90 FAMILY MEMBER; 1.
DR   Pfam; PF13589; HATPase_c_3; 1.
DR   Pfam; PF00183; HSP90; 1.
DR   PIRSF; PIRSF002583; Hsp90; 1.
DR   PRINTS; PR00775; HEATSHOCK90.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF110942; HSP90 C-terminal domain; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EEN67339.1"
SQ   SEQUENCE   660 AA;  74645 MW;  EB388F409B7A196B CRC64;
     LSLPRLLSES PAAEAEEADL HNIIKDTEKV TGSGEQHSFQ AETLKLLDIV AKSLYSDKEV
     FVRELISNAS DALEKLRYLS LTQGGSSELA VPLEIHLGTD LVQGTFTIQD TGVGLTQEEI
     IENLGTIARS GSKAFLSELD NRGQSSSAAS SIIGQFGVGF YSTFMVGDKV QVFTRSHQPD
     SPGYCWTSDG SGSYELAEAE GVQLGTKIVV HLKKECMQFA REDDIKEIVT KYSNFVNCPI
     YLNGKRLNTV EALWMLDAKN VTDEQHEEFY RFLANAYDSP RYRLQYQTDA PLNIRSLFYI
     PAHKPTMWDM SRQEGLGGVA LYSRRVLIQP KAETILPKWL RFVKGVVDSE DIPLNLSREL
     LQDSALIRKI RSVLTSRIVK FLGDQARRDA VKYQRFVEDY GFYLREGIVS TEDQDERESI
     AKLLRFESSA EPEGTLVGIE EYCKRMRPGQ RNIYYFSAPS RQLAETSPYF EALKKKDIEV
     LFCYEQYDEL TQVQMSALWG ERPKGHGMEN ERKPISPKKS AVIKPFTVLY AKNFTWIILP
     TILCLSIPNV THTRVSTRLE SHPAMVTVME MGAARHYLRT AFAGQSEAER WKFLQPTLEI
     NSSHPIMLKL SELKSSDPEL ARLVAEQVYD NALVAAGLIE DPRSMLNRLN ELLTRTLDKH
//