ID C3XXP0_BRAFL Unreviewed; 899 AA.
AC C3XXP0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 13-SEP-2023, entry version 75.
DE RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BRAFLDRAFT_63875 {ECO:0000313|EMBL:EEN67500.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN67500.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN67500.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN67500.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
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DR EMBL; GG666471; EEN67500.1; -; Genomic_DNA.
DR RefSeq; XP_002611490.1; XM_002611444.1.
DR AlphaFoldDB; C3XXP0; -.
DR eggNOG; KOG2177; Eukaryota.
DR InParanoid; C3XXP0; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00882; Ras_like_GTPase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR14241:SF31; -; 1.
DR PANTHER; PTHR14241; INTERFERON-INDUCED PROTEIN 44; 1.
DR Pfam; PF13676; TIR_2; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 16..56
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 160..319
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 109..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 502..553
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 115..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 102291 MW; 9FE166A603E6A830 CRC64;
MASGVESQIK EEFLVCQICF EDYREPKVLP CQHTFCKECL EKMVAKMGKL TCPNCRRECP
LPQNGVGGFP TSFFVNKLRD IVVNGGGVAL SSREDQSVTT SYHIDYREES PCRSTTARAD
NVASTGDTSR TAAQHTGSTP AGGHSGQSTR LRGLRQAPVQ EPRVFVIHAG EDKETFVRPL
VGKLQEKGLD KNDIFFDDLS IQPGDVIRER IMSTLSSESL KLAVVVVSAS FLNKSYWPRL
EFETCLQNNK HIFPIWVDAN EDNFKVFTIQ TRLDLVPSSY SSDSSDLDEE RSIEEKVCGA
ESSNAQSVEQ ILKDEKEKQQ DLLLFGVTQL ELLEKARGLL SVEMIEKRTL ELLDTLYQKG
LCILEVKKGC VILHIVPKNL STLDRFWRDY KSGQLSKLFT DRLVTDEMRA AAGMDLAVRV
VMLDQQYRQW TEYFNTQDMT QMVEKLPSLT MAPATLPVRK RPYVSPNISG SKKATKMTYE
GPTEVYKHVS SEEVREVKEK KAMTQREQVE REQIKLQEVE KRRQFLKQAE REKQMQAERL
KKLQQESLRE REKLLKYCFG DKHGPRFFTS IDIQDMQESD HGVRIGVFGP SGSGKSCLIN
TCERALGLTT EKTCRTDTNQ PEGTILLQEY LGDIGNFCLV ETRGFFNYDE KEFMIPALTN
ILYGRIKPGE KMDLKAMTTV DEDDSWDIFP NWLHAVVFVL SAHDPLLFNG AHEINLSLIH
EFMRLRGIAP ICVVTHVDQV KDKSQLDQIR TKASAATGSS LSHVYFTENY HPGHNERDFN
AELRAMEILN SALTVGERYV KIHKQQRQYQ EDARQAAVAQ SVAKAQSVAK ESIEDFFHRL
CHTKHIPHDK IEPVIVALKD QDVTTTSLLR DTWNDLKDEL PISSRMKTYI KGALFEDFP
//
