ID C3XZG0_BRAFL Unreviewed; 299 AA.
AC C3XZG0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE RecName: Full=DED domain-containing protein {ECO:0000259|PROSITE:PS50168};
GN ORFNames=BRAFLDRAFT_202645 {ECO:0000313|EMBL:EEN66724.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN66724.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN66724.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN66724.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR EMBL; GG666475; EEN66724.1; -; Genomic_DNA.
DR RefSeq; XP_002610714.1; XM_002610668.1.
DR AlphaFoldDB; C3XZG0; -.
DR STRING; 7739.C3XZG0; -.
DR eggNOG; ENOG502QRWB; Eukaryota.
DR InParanoid; C3XZG0; -.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IBA:GO_Central.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd08790; DED_DEDD; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR001875; DED_dom.
DR InterPro; IPR038856; DEDD/DEDD2.
DR InterPro; IPR049341; TRADD-like_N.
DR PANTHER; PTHR15205; DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15205:SF0; DED DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01335; DED; 1.
DR Pfam; PF20694; TRADD-like_N; 1.
DR SMART; SM00031; DED; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50168; DED; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 18..96
FT /note="DED"
FT /evidence="ECO:0000259|PROSITE:PS50168"
FT REGION 140..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 299 AA; 34087 MW; 73F3EF6B8C06E74B CRC64;
MASETNCCDQ ESCLSNYTLH DMFRIVGDQM TDRDLRVLNF LFTDILGEEQ RFKIETGLDF
FLALEKLNRC DETNFKQILH LLRIITRHDL NHYVQQRRRK TVNPDPVDKY LEDTSPRTYT
ITGTGQSKLC SPGKQTTLPS SICSYKPQEP ADMGPSGKRK ARGTGGGVQK KPANVFSTDI
RLRVRAEFCQ HDTALQGNIF SNKPSELERQ FERFSQANTI LKSRDLGAII CDIKFSELTY
LDAFWRDYIN GSLLEALKGV FITDSLKQAV GHEAIKLLVN VDEDDYEAGR VKLLMNLTQ
//
