ID C3Y020_BRAFL Unreviewed; 361 AA.
AC C3Y020;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Trypsin-3-like isoform X1 {ECO:0000313|RefSeq:XP_035669810.1};
GN Name=LOC118411560 {ECO:0000313|RefSeq:XP_035669810.1};
GN ORFNames=BRAFLDRAFT_277744 {ECO:0000313|EMBL:EEN66386.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN66386.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN66386.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN66386.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
RN [2] {ECO:0000313|RefSeq:XP_035669810.1}
RP IDENTIFICATION.
RC STRAIN=S238N-H82 {ECO:0000313|RefSeq:XP_035669810.1};
RC TISSUE=Testes {ECO:0000313|RefSeq:XP_035669810.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; GG666477; EEN66386.1; -; Genomic_DNA.
DR RefSeq; XP_002610376.1; XM_002610330.1.
DR RefSeq; XP_035669810.1; XM_035813917.1.
DR STRING; 7739.C3Y020; -.
DR MEROPS; S01.079; -.
DR KEGG; bfo:118411560; -.
DR eggNOG; KOG3627; Eukaryota.
DR InParanoid; C3Y020; -.
DR OMA; SINQAGC; -.
DR OrthoDB; 2996498at2759; -.
DR Proteomes; UP000001554; Chromosome 3.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00112; LDLa; 2.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 2.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24252; ACROSIN-RELATED; 1.
DR PANTHER; PTHR24252:SF13; TRANSMEMBRANE SERINE PROTEASE 12; 1.
DR Pfam; PF00057; Ldl_recept_a; 2.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00192; LDLa; 2.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS01209; LDLRA_1; 2.
DR PROSITE; PS50068; LDLRA_2; 2.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Hydrolase {ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000001554};
KW Serine protease {ECO:0000256|RuleBase:RU363034};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..361
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041116425"
FT DOMAIN 130..359
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT DISULFID 21..33
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 28..46
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 40..55
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 82..97
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 361 AA; 38203 MW; 9FB21431AB83D9DA CRC64;
MIWCLLLLAL AARGDAWLFS CSASDFQCSN GNCIPGSWEC DGEADCSDGS DEASCSGGGT
CQQGVHFFCA NGLYCIDSNW VCDGDNDCGD MSDEQNCGGG STGTTGTTAP ITSFTGDCGQ
PAISPQNVRV VGGVQAVQGS WPWQASLKLY GGHVCGGQII APNWIVTAAH CVDGQSNPSQ
WRVSLGSHRR TSTDSTQQDF SVTRIIMHES YDSNRINNDV ALMKLSGNAQ FNNYVSPICL
PTQDVAAGTN CVTTGWGDTG SGASTYLMQA TVPIMEWNKC NSAQYMNGAI TDKMICAGYD
QGGKDACQGD SGGPLVCNYS GKWTLDGIVS WGYGCAQAYK PGIYTRVTQF VSWINNKMAS
N
//
