ID C3Y1A9_BRAFL Unreviewed; 1671 AA.
AC C3Y1A9;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Folate receptor-like domain-containing protein {ECO:0000259|Pfam:PF03024};
GN ORFNames=BRAFLDRAFT_123559 {ECO:0000313|EMBL:EEN65649.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN65649.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN65649.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN65649.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Belongs to the folate receptor family.
CC {ECO:0000256|ARBA:ARBA00007932}.
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DR EMBL; GG666480; EEN65649.1; -; Genomic_DNA.
DR RefSeq; XP_002609639.1; XM_002609593.1.
DR eggNOG; ENOG502RYYP; Eukaryota.
DR InParanoid; C3Y1A9; -.
DR GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR GO; GO:1902444; F:riboflavin binding; IBA:GO_Central.
DR GO; GO:0032217; F:riboflavin transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR InterPro; IPR004269; Folate_rcpt.
DR InterPro; IPR018143; Folate_rcpt-like.
DR PANTHER; PTHR10517; FOLATE RECEPTOR; 1.
DR PANTHER; PTHR10517:SF22; RETBINDIN; 1.
DR Pfam; PF03024; Folate_rec; 5.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1671
FT /note="Folate receptor-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002935023"
FT DOMAIN 35..202
FT /note="Folate receptor-like"
FT /evidence="ECO:0000259|Pfam:PF03024"
FT DOMAIN 239..409
FT /note="Folate receptor-like"
FT /evidence="ECO:0000259|Pfam:PF03024"
FT DOMAIN 438..605
FT /note="Folate receptor-like"
FT /evidence="ECO:0000259|Pfam:PF03024"
FT DOMAIN 1019..1186
FT /note="Folate receptor-like"
FT /evidence="ECO:0000259|Pfam:PF03024"
FT DOMAIN 1234..1391
FT /note="Folate receptor-like"
FT /evidence="ECO:0000259|Pfam:PF03024"
FT REGION 615..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 686..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1196..1223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1399..1520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 696..817
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1199..1220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1408..1518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1671 AA; 188018 MW; C657BD331C80DB12 CRC64;
MASLLHLLAV LSVLGCSFAD HPGHVDYPGG LQTGCLQGEK HKDAPSPESG LGVCKDYSDS
SCCSADIGQQ LSVTPIVKVD GFRWDNCGTL SKRCQDFMVN VECFYRCSPS LPTWAAPYPS
AVRGVPVCMQ FCDDWMEACR EDMTCADNWI TGWKIEDGEL NKCRSEERCR TFAQVFRNGR
GLCESIWGQS FTYESTPDTP CLDFRFPPTE GQITVPEPGT ESVEPAFKRQ DECIIDAVDF
HKKKPSPEPK LNACRNYRQD SCCTTEIDND MVNRPIRKVG QMNWDTCGPL SPRCEEFLID
SECFYQCSPL LNKWRVPGVD PAADPFTPVV EGIPLCSHFC DGMFNACKFD RTCAVNWATD
WDFSTGENKC RPDSKCELIK DVFKNAKAMC ESVWGSAFTY VSNRNAPCLD PTAHPSEQVT
KPRKVAVAAA ESEDKWGCLG GRTNKRTPGP EPDLQVCSEY SMNSCCSAEF DQQLRMSPVV
KIDKFYMNRC GTMSPRCEQF GLAMNCHYHC DPMIYRYGKR GHPWAVQNIP ICSSFCDDFF
DACRDDLTCA ESQATDWYYS PEGINNCRPD SKCRTFAEVY VDGRGLCNNI WGDSYVYTED
DDTCINIMSI GSQTRASDAE EHNPHADHHH DDGHGHSDMS HADSDSWACV RHDDPHHKMY
GDAQTLCETF FGSEFQYNST DRCVDIPLHS SPAQDQAHHA SHDRADHDHH EHEGHHSSEE
GHSHDTHHSG HSPDSHGDHG DDEHHHGDDE HHHGHDEHHH GHDEHHHGHD EHHHGHDEHR
HGDTVDHGHE THHGDNDPAA HGEHDHRSHH HGSRDDVRSV QPLSWPVHQC VWQTGLKDHD
GLVKTCSFQK RHYSSVLRLA YSGGLILANC TECCKRWYFT INGIECQKPG GIDAIVMKMG
HQGNMVHQHQ QFEGFCDKVG AGVLDVELRV QDCTEHMPHH GHSGAMDPGD AQTGGHCFSR
IMVFKNAKAM CESVWGSAFT YVSNRNAPCL DPTAHPTEQV TKPRKAVVAA AESEDKWGCL
GDRKHKRTPG PEPDLQVCSE YSMNSCCSAE FDQQLRMSPV VKIDQFYMNR CGTMSPRCEQ
FRLAMNCHYH CDPMIYRYGK RGHPWAVQNI PICSSFCDDF FDACRDDLTC AESQATDWYY
SPEGINNCRP DSKCRTFAEV YVDGRGLCNN IWSDSYVYTE DDDTCINIMS IGSQTRASDA
EEHNPHADHH HDDGHGHSDM SQADSDSWAC VRHDDPHHKE YPTPEPDLQV CSPYAYGSCC
TVEHDHHLAV RPVPGVHNFS WNRCGTLSPQ CENFMIDLEC FNSCSPDIRR LSIPTDSGSA
IPVCASFCDR WFSACRNDVT CVANWRSDWD MDDNNRNNCP EGSSCKTFDE MYGDAQTLCE
TFFGSEFQYN STDKCVDIPL HSSPAQDQAH HASHDHADHD HHEHEGHHSS EEGHSHETHH
PGHSPDSHGD HGHDEHHHGH DEHHHGHDEH HHGHDEHHHG HDEHHHGDHG HETHHDDDPA
AHGEHDHGSH HRGSRDDVRS VQPLSWPVHQ CVWQTGLKDH GGLVKTCSFQ KRHYSSVLRL
AYSGGLILAN CTECCKRWYF TINGIECQKP GGIDAIVMKM GHQGNMVHQH QQFEGFCDKV
GAGVLDVELR VQDCTEHMPH HGHSGAMDPG DAQTGGHCFS RIMVEEVGMS P
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