ID C3Y4L1_BRAFL Unreviewed; 566 AA.
AC C3Y4L1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 72.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=BRAFLDRAFT_73882 {ECO:0000313|EMBL:EEN64668.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN64668.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN64668.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN64668.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; GG666486; EEN64668.1; -; Genomic_DNA.
DR RefSeq; XP_002608658.1; XM_002608612.1.
DR AlphaFoldDB; C3Y4L1; -.
DR ESTHER; brafl-c3y4l1; Cholinesterase-like.
DR eggNOG; KOG4389; Eukaryota.
DR InParanoid; C3Y4L1; -.
DR GO; GO:0004104; F:cholinesterase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR019819; Carboxylesterase_B_CS.
DR InterPro; IPR000997; Cholinesterase.
DR PANTHER; PTHR45570; CARBOXYLIC ESTER HYDROLASE; 1.
DR PANTHER; PTHR45570:SF1; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR PRINTS; PR00878; CHOLNESTRASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 22..566
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5005125001"
FT DOMAIN 29..554
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT REGION 90..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 566 AA; 62798 MW; 9364699717A6E3B8 CRC64;
MATTTFSKLA VFAALVFVGQ AALVTKPDGP IVRTRHGDVR GMYVEEGAIF LGLPFGDPPV
GELRWKPPRA YNKSWAPGVR DGTVPGPACR QTSCGPNSTD SQHTCNRDKN KTQSEDCLYL
NVFVPRSVLA NSTVRLPVMC WFHGGNYQYG TGAALIYDGR ILANKTNTVV VTTNYRLGVF
GYLVTGEGED DARGNYGTLD QIEALKWVQQ NIADFGGDKD KVTVFGQSAG SDSIAVLLTS
ARAADLFHQG IMLSVPFSIP LKTQSEAIRY GNDFTKFANC STGDMKCLRS KPADEILQAQ
KKVSKSIVDP FRLLELFMQW GPSVDGDILP RPVVESFAKG QFQRKPFIIG TVREDALYYI
YSAFNKPVSK LELDGAVLAF LHGKGPAALH EYNPPQTSDY RPFLSQAVTD WIFECPTRNV
IRNAALNGET DVWLYVFDHA FSFKTFWHGH AYCQGHVCHG EDIPFVFQTP LLINLTFTPD
EQVLADTMAY HYGNFAHTGD PNKASPNVYT TGNVLKSPLN WPRYNKGNLF PNMNFTTPQS
VIVKDYNKAK CDFWDKENIY SATNKG
//
