ID C3Y5J1_BRAFL Unreviewed; 504 AA.
AC C3Y5J1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE RecName: Full=ETS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BRAFLDRAFT_87894 {ECO:0000313|EMBL:EEN64238.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN64238.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN64238.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN64238.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR EMBL; GG666487; EEN64238.1; -; Genomic_DNA.
DR RefSeq; XP_002608228.1; XM_002608182.1.
DR AlphaFoldDB; C3Y5J1; -.
DR STRING; 7739.C3Y5J1; -.
DR eggNOG; KOG3804; Eukaryota.
DR InParanoid; C3Y5J1; -.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR003118; Pointed_dom.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF190; ETS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00178; Ets; 1.
DR Pfam; PF02198; SAM_PNT; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SMART; SM00251; SAM_PNT; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR PROSITE; PS51433; PNT; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019}.
FT DOMAIN 116..202
FT /note="PNT"
FT /evidence="ECO:0000259|PROSITE:PS51433"
FT DOMAIN 412..494
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 273..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..344
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 504 AA; 57407 MW; 268B3ABC211126E3 CRC64;
MADMTVWRGA MSARSRVFTK FTASCTREGS TFVTVMAESL TQAIDDTTLD LGQFLSNFPI
PTPTQFAIPQ PSDAVFPTPP TSPPNMTSTW GPVKSELPSS CTLQSEQASF TELQTAHANY
MPIQNQFNWC NSHPMNWSYQ QVRGFLTWAV AEYELPPHEI NFEHFRVNGA KLCMMSREEF
SLLCPNYGDI LYLSIGKVLE EAQYLYDPTP AFCEGPSDTT MSESVRAMHE EMMNMDFIQA
PVDDLPMQDL FPDCGGITAD DIDVNDKFED VNVELSDFPP SPTASDESYS SMSPGPTSPY
YCSSESDYSS GDRTLGNLFM PRYETSDGDS DHDSYGSSPR RSYTDELHMY DDSDKEVKPT
VDFSVQNAPI NMKIKPAGAP ERRARGRPRK VRTVTEEMLT TGKRGRQHSK GNHLWEFVRD
LLKNPSTNPK VIKWEDRRDG IFRFVQSEAV ANMWGRKKNN PNMTYEKLSR AMRYYYKRHI
LERVDGKRLV YRFGTEAKGW RENE
//
