ID   C3Y675_BRAFL            Unreviewed;       264 AA.
AC   C3Y675;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN   Name=LOC118413346 {ECO:0000313|RefSeq:XP_035672580.1,
GN   ECO:0000313|RefSeq:XP_035672581.1};
GN   ORFNames=BRAFLDRAFT_96598 {ECO:0000313|EMBL:EEN64472.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN64472.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN64472.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN64472.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
RN   [2] {ECO:0000313|RefSeq:XP_035672580.1, ECO:0000313|RefSeq:XP_035672581.1}
RP   IDENTIFICATION.
RC   STRAIN=S238N-H82 {ECO:0000313|RefSeq:XP_035672580.1,
RC   ECO:0000313|RefSeq:XP_035672581.1};
RC   TISSUE=Testes {ECO:0000313|RefSeq:XP_035672580.1,
RC   ECO:0000313|RefSeq:XP_035672581.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|ARBA:ARBA00006840, ECO:0000256|RuleBase:RU361218}.
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DR   EMBL; GG666487; EEN64472.1; -; Genomic_DNA.
DR   RefSeq; XP_002608462.1; XM_002608416.1.
DR   RefSeq; XP_035672580.1; XM_035816687.1.
DR   RefSeq; XP_035672581.1; XM_035816688.1.
DR   STRING; 7739.C3Y675; -.
DR   KEGG; bfo:118413346; -.
DR   eggNOG; KOG3882; Eukaryota.
DR   InParanoid; C3Y675; -.
DR   OMA; CHTAILN; -.
DR   OrthoDB; 2964111at2759; -.
DR   Proteomes; UP000001554; Chromosome 4.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR000301; Tetraspanin_animals.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   PANTHER; PTHR19282; TETRASPANIN; 1.
DR   PANTHER; PTHR19282:SF557; TETRASPANIN; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; Tetraspanin; 1.
DR   PROSITE; PS00421; TM4_1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361218};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001554};
KW   Transmembrane {ECO:0000256|RuleBase:RU361218};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        56..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        87..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        214..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
SQ   SEQUENCE   264 AA;  29734 MW;  BD745F7AACE8DC02 CRC64;
     MVLEGSATCL KYLLFAFNFM FWLSGCAILG VAIWLRIDVQ TMQYVRVGED LETFYIGTYV
     LIAAGALVML VGFLGCCGAI MESPWLLASF FAFLVLIFSA EVGGGAWAYL HRSKLEDYVR
     EEFQLIVQTR YNQDTYETTT KLWDQLQISL RCCGGEDMTD WNLSFWGSYN PRDVPDSCCV
     RQERRCGRWG LTKKIGMYRQ GCSSKMVSFF SSRLLIIMCV GLGVAILQLM GMIFSLMLCC
     ALRGRRGSEP IDNDSNSKPP AVVV
//