ID   C3Y996_BRAFL            Unreviewed;       684 AA.
AC   C3Y996;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 62.
DE   RecName: Full=Thioredoxin domain-containing protein {ECO:0000259|PROSITE:PS51352};
GN   ORFNames=BRAFLDRAFT_118662 {ECO:0000313|EMBL:EEN63152.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN63152.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN63152.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN63152.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
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DR   EMBL; GG666492; EEN63152.1; -; Genomic_DNA.
DR   RefSeq; XP_002607142.1; XM_002607096.1.
DR   AlphaFoldDB; C3Y996; -.
DR   STRING; 7739.C3Y996; -.
DR   eggNOG; KOG0190; Eukaryota.
DR   InParanoid; C3Y996; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 2.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR46497; THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11; 1.
DR   PANTHER; PTHR46497:SF1; THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11; 1.
DR   Pfam; PF00085; Thioredoxin; 2.
DR   SUPFAM; SSF52833; Thioredoxin-like; 2.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        33..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          315..430
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          575..684
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          452..528
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1..24
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        575..589
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        602..616
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        629..656
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   684 AA;  78164 MW;  49E542CDFC2639CC CRC64;
     MVERQVAKHN AEEENTEETK RTRLTEKRAK KRAMVRLAAI RLVLCLLVGL FFYIVKASRS
     SHYAVNPSAR LFHPMSPVRE FRSGDVQTMR KLVAHSELSM VMFYAPWCAE SRLAAQEYVE
     AGKELHKEIF FAAINCWEYA GECRKKFAFQ KFPKFFVYNS RLEGIEYNGP VTTKHIVKFL
     RRVASPVTYV RNLEDLVFFC ALQDTGVLAY FDFSGWRPTL GYLHYYLAAQ NALEIEPFHG
     VNFGVITSLE VAGLVKIKEP RTVVMVRALN DTLVYPDTRN FSHQEILAWV EENKVKTVQW
     LPLSGMKSLQ LSTELYAGPS LLYFTPDNPD GESTSVAMDV LLLYYAPWCG ACSALSHIWL
     VLASYFKRAS NLVLARINGD KNDLPWEFTV PAYPTVIFFP AFRKDMSVKY PDNLPMTLPN
     LAEFVLAHAR RRNRPRSNIT GHKVTADCQE KTEASNLKIQ SLERELSSMK EEIETLRTQA
     QKLQDAFHIV KGANIRLNAE NREKDLRIEA LRKSEAKLKE ALKEKEVRLL QADVFMRALQ
     EGSVKATSEN VLLKMQVSAL QQALDSIYNV MEADKKQNPT ERKDPRHSVD AASPPTPVNR
     KDRQGEGSSQ VQKDSLKDAP QFRKVAQPVR EGGRQREHFH VHSARGKRRE DTEGGKQRVS
     VVPTAKIQHT QVLHTHENNQ EDYT
//