ID C3Y9G5_BRAFL Unreviewed; 462 AA.
AC C3Y9G5;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEN63221.1};
GN ORFNames=BRAFLDRAFT_67991 {ECO:0000313|EMBL:EEN63221.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN63221.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN63221.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN63221.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC 1.A.6) family. {ECO:0000256|RuleBase:RU000679}.
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DR EMBL; GG666492; EEN63221.1; -; Genomic_DNA.
DR RefSeq; XP_002607211.1; XM_002607165.1.
DR AlphaFoldDB; C3Y9G5; -.
DR STRING; 7739.C3Y9G5; -.
DR eggNOG; KOG4294; Eukaryota.
DR InParanoid; C3Y9G5; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015280; F:ligand-gated sodium channel activity; IBA:GO_Central.
DR GO; GO:0035725; P:sodium ion transmembrane transport; IBA:GO_Central.
DR Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR InterPro; IPR001873; ENaC.
DR PANTHER; PTHR11690:SF283; -; 1.
DR PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR Pfam; PF00858; ASC; 2.
DR PRINTS; PR01078; AMINACHANNEL.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU000679};
KW Ion transport {ECO:0000256|RuleBase:RU000679};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW ECO:0000256|RuleBase:RU000679};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000679};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|RuleBase:RU000679}.
FT REGION 130..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 51577 MW; E422558D226A0367 CRC64;
MEEKTGGFLG TLREYGENTS AHGIPRAVTT KSLPRRLFWT CLFLASFSYF CSQAYDLVNK
YLDYPVTTDI KIEWSELEFP AVTICNANPL RFSELRKLGH EGFQNAGFIP KPDRTPQNNQ
GNAVNNIAAA AGGRPQQKQP TTVPPTTTTR TETTTPGDYE DYEDYDYDYD DHHEDFKTAN
TFMGLIANMN STTRQAIGHQ ARDFIQECQF DGRACSPKNF SVFTDSTYGN CFTFNKAIGN
TAPQRSTSAG PLNGLSLILY IQQEEYIPSL TEKAGARVVV HSPDRWPFPE FEGFDASPGF
LTSAGLRLNC LVTCHQQHMV SVCGCADPSF KATVNTAFCD SVTTTVPRTE QAYDKKRTSS
RCRRNLLKLN IYYEALNYEQ ISESPGYEEE SLLGDLGGQL GLWVGMSLLS AMEVVEIFAD
LFAIIFKKFS SKEMKSSKKI DVAPREKIDA NDLALSYIKG NM
//
