ID C3YAW2_BRAFL Unreviewed; 1372 AA.
AC C3YAW2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN ORFNames=BRAFLDRAFT_131068 {ECO:0000313|EMBL:EEN62563.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN62563.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN62563.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN62563.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
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DR EMBL; GG666495; EEN62563.1; -; Genomic_DNA.
DR RefSeq; XP_002606553.1; XM_002606507.1.
DR eggNOG; KOG4308; Eukaryota.
DR InParanoid; C3YAW2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049352; Rost.
DR PANTHER; PTHR46312; NACHT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46312:SF1; NACHT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13516; LRR_6; 3.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF21534; Rost; 1.
DR SMART; SM00367; LRR_CC; 4.
DR SMART; SM00368; LRR_RI; 4.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1153..1171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1192..1217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1229..1248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1255..1275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1295..1328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 264..386
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REGION 1..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 118..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1372 AA; 154650 MW; 6C8C0A48B928C855 CRC64;
MRRQLPIGIG QSKETLQKRR KSLDSRTCPG EPAGLSRTTD MMEESPCLKQ TSDKRRPMLL
SPSLKIEADV SSDSGTEVHS DEHEEGGQCL SPKSLASPSS YTSLASISPM PSGVDLKSLL
DDSFPHSPNA SLGQEFTELT DSSSKPPRRA IDILIGGERF VLGQSSSDTS PHSPFRAYAE
KGEVPSATSD TSIHDLRDEL AKHYIRNMKQ ITPLPWNSKF LVDVRDVSLH YEVLQEGKRP
GDMHRVRLKR FEDVFECKGL PGPRRIFCQC IPGVRKATLL NKVPVEWSRG RWMFLVERFQ
LLFSINLLDV AAEDTLWDTL RSQLPKPLSV ASIESVKAFL LDEETQWSTL FLIDGYDERA
DINGDIRKLI QGRLFPDSCV IVFARPFHYP DLMQWMDTRV EISGFSIRSA YRLLHNYFPD
NPHKAAGLIA ALKQYENVTA VDVKRTSLHI WLLCVLWDDN PKKPFPETMT RLYSEFLSCV
IRHHKELTRE EIDVEAVLNP VGKIAMDGLL GKKAIFNLCD LEPVQDGINL LLELGILRSG
SKCVDIMAPS SLLFSHTTMQ EFVAGRYLAS QLQPHDSTHE HLPFNTVKDA LALENVILFA
SGTTGAAGKV ILSHLSKIYA DELREHEEAY YREQMPTAEF EEFRSFVVLC LRCLYESPVR
KELCQCCMLD FLSRRVRLDW MGVPSQESVA LQCFLCLTAT EGTKSAVTDL TLSFHDYSLK
KPEYLFNILH YVPHLRNLTV HLGTCLEKEC EDLSLLDQPL GCLRELCSVH ITGDARRFTG
LSFAFLKPSE NLTSITMQDV QLGSRLARVA ANFKYLPCLT TLKLQDCGLT GEDVTAMSEY
LYHVPLEELD VSFNELGNEL CSLVTKLVDL PSLRILRMCD VSATFSTIET IGKALEHINQ
LEELYLAQNE VDAWNYRGCW EDLVQNVCHL PKLRVVDVSR CLIGSHNLAL LIKGLIHTMV
ESINVAYNEA TNETMEAIEE NLPQLPYLKT LNVSGNEISF HGVYYFGKAL HQARNLTSLN
VSYNELADVA VADLAGRLHQ VAGHLRALDI SSNPVTEEGL KNFASSMEPM IALRQLNMSG
AGWQSFHLSD EAAVSIAQLL GRLPSLERLE LRWITMQHEG FQAVVRAAMK HPKLQELCIP
TDSNRWITFY TNWAYTAFTL HFCWAAAVCV LDYRSAAENH RGKLRGGPPA KMALKIGWVI
YNVAMSNAFM VSAEYWLSPF PVTFGFRSFL RHGLNSIMAV TDIIVSGIPS RLDHVVHTVL
FAVIYNTFLV LYWLFDCRGY DGKPYVYSFA DFNTVPLQAF VILAGSNFII LPAAHGLVCL
LYQIRLVLLG NFKERKARRV IELAPWQKRI LPIEVSEDVI MDVSSRTDEQ IV
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