ID   C3YFR4_BRAFL            Unreviewed;       395 AA.
AC   C3YFR4;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   24-JAN-2024, entry version 50.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   ORFNames=BRAFLDRAFT_80321 {ECO:0000313|EMBL:EEN60719.1};
OS   Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC   Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC   Branchiostomatidae; Branchiostoma.
OX   NCBI_TaxID=7739;
RN   [1] {ECO:0000313|EMBL:EEN60719.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN60719.1};
RC   TISSUE=Testes {ECO:0000313|EMBL:EEN60719.1};
RX   PubMed=18563158; DOI=10.1038/nature06967;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA   Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA   Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA   Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA   Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA   Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA   Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA   Satoh N., Rokhsar D.S.;
RT   "The amphioxus genome and the evolution of the chordate karyotype.";
RL   Nature 453:1064-1071(2008).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GG666510; EEN60719.1; -; Genomic_DNA.
DR   RefSeq; XP_002604708.1; XM_002604662.1.
DR   AlphaFoldDB; C3YFR4; -.
DR   STRING; 7739.C3YFR4; -.
DR   eggNOG; ENOG502QSKR; Eukaryota.
DR   InParanoid; C3YFR4; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR16059; ANTHRAX TOXIN RECEPTOR; 1.
DR   PANTHER; PTHR16059:SF25; THROMBOSPONDIN-RELATED ANONYMOUS PROTEIN; 1.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..395
FT                   /note="VWFA domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002933693"
FT   TRANSMEM        268..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          43..128
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   395 AA;  44984 MW;  95C39D1673C5E122 CRC64;
     MANFYFKTFV QFGILLLVGS DTSTLVGALD IKPKSQSCRG AFDMYFVLDR SASVTPKNFR
     EETVDFVEKI VNSFHSPKVR FSFITFSDDA SVVMELSNDP DVIKHGLSHL RQIDTYGGTF
     MSHGLRKADK SRSLGATVFA IGVGNYDDVQ GTAKIREMFD TLQTHSVQVK ADYWWWLTRS
     WLDHDLGHDL DSFVVRPRSL YAELNKSRLA SVFEVDIWGN GFRKTDNISN VFCNFRLNDT
     DNQVSVNGKT FISSNVTIEA LDCTPTDVAA IVLPLFFLLL LLALLLLWWF WQLLCCYVEE
     PKPKWPKVSA SYYGGRGAGG MSRMQGKLRT CRDYLLKQYH RVDIMRPRPG DKLITSQPRR
     QPANHSRLFP NSLPAIAFNM SCWTMLETVF MMPHG
//