ID C3YHU2_BRAFL Unreviewed; 759 AA.
AC C3YHU2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Death domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BRAFLDRAFT_71642 {ECO:0000313|EMBL:EEN60079.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN60079.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN60079.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN60079.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
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DR EMBL; GG666514; EEN60079.1; -; Genomic_DNA.
DR RefSeq; XP_002604068.1; XM_002604022.1.
DR AlphaFoldDB; C3YHU2; -.
DR eggNOG; KOG0032; Eukaryota.
DR InParanoid; C3YHU2; -.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01671; CARD; 1.
DR CDD; cd01670; Death; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR032171; COR.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR039788; NOL4/NOL4L.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR12449; DEATH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12449:SF18; DEATH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF16095; COR; 1.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF08477; Roc; 1.
DR SMART; SM00005; DEATH; 1.
DR SUPFAM; SSF47986; DEATH domain; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
PE 4: Predicted;
FT DOMAIN 615..685
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT DOMAIN 657..750
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
SQ SEQUENCE 759 AA; 86540 MW; 4D3DC0440F8589E8 CRC64;
MNRRDFLQAA QDGDVEKVRR WLEEGLDVNT KDYINKRPVD VAAGLGSDTQ LLLETETRKQ
AEYSELVSSV GSEEGTTVKL FLCGDGQVGK TSLRAILKKT GFIVGALWNI RRKFRRQDVF
NPTPGVHVSI EVVPGIGRLS LHDFAGQAQF YVTHAMLLRT TNAIFPVVYK ITDGEDEQKQ
QVHGWLSFIH CSNADPTNKP RIVLIASHAD KLQDRKAGRR QAKALVEYYR KLFQESLIVS
QEVFLINCLE AGSPEIQRLR EVLGTFKDDM LKQRTQIPKV CVQLSKTIEG WREERKTFPV
MGWQDYLAAV RQACIYIEER IAELASSYLH DEGEIIYLRH QADSLVVLDP QWLFTSVIGS
LLAPDNFPIV KIARTAEDYV TLEELTRVFS AVADIPLLIK LLQDFQLCHT YDEVTLIIPS
LLQQEMEEAA WSPVSSKAVY FGLQIRGRTE IDSFSCDLFP RLQTLLMQAH PDKLSRPLLW
KNSAKCTDKK ADALLQITQD KRQLNIFVRS NDGNREDCNS IMDLLKDMTY RLLHETSPGA
RSRDMVLSAL DLREHSREPH AYSRAEVEAA AAKGENLVHP ERNVPEKVKD LRLKLGYMEG
YMSKCFGKVI RGTSADWDNL AWELNFEENE IRVIREMEHD CDRRCREMLE RWRNREGEAA
NVQALKKALI KIGHRLTAET LEVCTLVNGC NLSRERLERN KHLKTSRTPQ DAARELLDIL
EAKGERACVK FYAVLKLCDK FAASLIVEEE MSEEGATAS
//
