ID C3YIE0_BRAFL Unreviewed; 1179 AA.
AC C3YIE0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 80.
DE RecName: Full=AP-3 complex subunit delta domain-containing protein {ECO:0000259|SMART:SM01354};
GN ORFNames=BRAFLDRAFT_276908 {ECO:0000313|EMBL:EEN59873.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN59873.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN59873.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN59873.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613}.
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DR EMBL; GG666515; EEN59873.1; -; Genomic_DNA.
DR RefSeq; XP_002603862.1; XM_002603816.1.
DR AlphaFoldDB; C3YIE0; -.
DR STRING; 7739.C3YIE0; -.
DR eggNOG; KOG1059; Eukaryota.
DR InParanoid; C3YIE0; -.
DR GO; GO:0030123; C:AP-3 adaptor complex; IBA:GO_Central.
DR GO; GO:1904115; C:axon cytoplasm; IEA:GOC.
DR GO; GO:0010008; C:endosome membrane; IBA:GO_Central.
DR GO; GO:0098830; C:presynaptic endosome; IBA:GO_Central.
DR GO; GO:0043195; C:terminal bouton; IBA:GO_Central.
DR GO; GO:0048490; P:anterograde synaptic vesicle transport; IBA:GO_Central.
DR GO; GO:0006896; P:Golgi to vacuole transport; IBA:GO_Central.
DR GO; GO:0098943; P:neurotransmitter receptor transport, postsynaptic endosome to lysosome; IBA:GO_Central.
DR GO; GO:0006623; P:protein targeting to vacuole; IBA:GO_Central.
DR GO; GO:0016182; P:synaptic vesicle budding from endosome; IBA:GO_Central.
DR GO; GO:0048499; P:synaptic vesicle membrane organization; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.450.50; Longin domain; 1.
DR InterPro; IPR017105; AP3_complex_dsu.
DR InterPro; IPR010474; AP3D_dom_metazoa.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR PANTHER; PTHR22781:SF12; AP-3 COMPLEX SUBUNIT DELTA-1; 1.
DR PANTHER; PTHR22781; DELTA ADAPTIN-RELATED; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF06375; AP3D1; 1.
DR SMART; SM01354; BLVR; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
FT DOMAIN 664..804
FT /note="AP-3 complex subunit delta"
FT /evidence="ECO:0000259|SMART:SM01354"
FT REGION 624..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..940
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..767
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..859
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 894..914
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 915..935
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1179 AA; 132615 MW; A51E57D7A1D5AD42 CRC64;
MALKKVKGSL ERVFDKNLHD LVRGIRNHKD DEAKFIAQCI DEIKQELRQD NIAVKANAVA
KLTYLQMLGY DISWAAFNVI EVMSSNKFTF KRIGYLAASQ SFHEETEVLM LTTNMIRKDL
SSQNQYDAAI ALNGLSCFMT PDLARDLAND VMTLMTSTRP YIRKRAVLIM YKIFLKFPEA
LRPAFPRLKE KLEDPDPGVQ SAAVNVICEL ARKNPKNYLS LAPVFFKLMT SSTNNWVLIK
IIKLFGALTP LEPRLGKKLI EPLTNLIHST SAMSLLYECI NTVIAVLISL SSGMPNHNAS
IQLCVQKLRI LIEDSDQNLK YLGLLAMSKI LKTHPKSVQA HKDLILQCLD DKDESIRLRA
LDLLYGMVSK KNLMEIVRKL MIHMDKAEGS MYRDELLSKI VQICSQNNYQ YITNFEWYVS
VLVELTRVEG TRHGSVIASQ MLDVAIRVKA IRAFAVEQMA QLLENSHIVA SSAQRNGICE
VLYAAAWIAG EFSEHLRDPK GTLEDMLRQK VTSLPGHIQA VFVQNIMKLY AAILVKYEED
EDNDGIREVS DLLVEKLPMF VQSGDLEVQE RACCILQLMK YVKKLQDKDV SCADEVSALF
AGELNPVAPK AQRKVAVPEG LDLDKWINDP PSESSDEEGP ANSLFIPDDS RMMNESLTRQ
VEELSDDELE RRREIRRAET QNNPHYLKLG GPAKGSKYQE VVNVEDIPVA NIDLSVPLYV
PGTKRLSDKY LEAERQARKR EKKRRHGKKS KRRHKSESEE DMPVVHKVDI MGGEMPEGAT
ESGDEGNQEL DDNDPHKLLD IDLDRPLEAD EKLPVRTHRI VSPSAEERPV EEKKKHHRKD
KEKEKKKKEK EKKDDLDFWL SGQDAPVAVE VTAPEAGAAA DVDSDAEDTS RHKKKKEKKA
KKEKKEKKDK KEKKKKSKAA DEDEEIGRRD GFEELASDAP ALPPMSSYRL LAEDSNIKMT
YETRVQPQQG QQLIVSVIFT SLAQHHLKSL EFNVMDSLNT KMDRLPGATT HDGVPVPFQL
PPNSFNEGQF AFQVQSINVA QKLRGTLTYT IKTEESSTSE KLDFKLYLPC TAFLIATPCS
SDAFARLLQG GDLSSKYSIK LPNSGVPFSH ILAKVCFYGH FAIVEQIDQS ASLYSCSTQG
HHICLLVKAN GGGDVSIDGK CADGSLLSNV MEEIKVTAS
//
