ID C3YIJ3_BRAFL Unreviewed; 479 AA.
AC C3YIJ3;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Histone acetyltransferase KAT6B-like {ECO:0000313|RefSeq:XP_035698342.1};
GN Name=LOC118431328 {ECO:0000313|RefSeq:XP_035698342.1};
GN ORFNames=BRAFLDRAFT_131253 {ECO:0000313|EMBL:EEN59926.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN59926.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN59926.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN59926.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
RN [2] {ECO:0000313|RefSeq:XP_035698342.1}
RP IDENTIFICATION.
RC STRAIN=S238N-H82 {ECO:0000313|RefSeq:XP_035698342.1};
RC TISSUE=Testes {ECO:0000313|RefSeq:XP_035698342.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG666515; EEN59926.1; -; Genomic_DNA.
DR RefSeq; XP_002603915.1; XM_002603869.1.
DR RefSeq; XP_035698342.1; XM_035842449.1.
DR STRING; 7739.C3YIJ3; -.
DR KEGG; bfo:118431328; -.
DR eggNOG; KOG2747; Eukaryota.
DR InParanoid; C3YIJ3; -.
DR OMA; HTHEDAT; -.
DR OrthoDB; 3921326at2759; -.
DR Proteomes; UP000001554; Chromosome 15.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd15527; PHD2_KAT6A_6B; 1.
DR CDD; cd09583; SAM_Atherin-like; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR048589; SAMD1-like_WH.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12247:SF139; ATHERIN-RELATED; 1.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR Pfam; PF00628; PHD; 2.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF21524; SAMD1_WH; 1.
DR SMART; SM00249; PHD; 2.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001554};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 227..286
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 283..333
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 411..459
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 105..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 479 AA; 52773 MW; D15E5B15D0DA310E CRC64;
MSAPKYTEWI LETIDSLRKR KARPDVDRIC HMVERRHGVK SAEIAADLER LVDADIVIKV
EYKGSTSYRN AAKWKKSHLS GVQLNSQRAS HKVLAAVRGL FAVGPGGSRA TTGGSEGEEA
GSSSTRVATQ GVTPTDIENY LRQEDSNTNL TGEHLLTVLQ REVEAARLLR SRTGEYVLPG
GQKPASSPKK TSPAGAAAPA RFTKRKRIKK THGPDFEQEP LVKSPSDPRC DYCLLTSECN
RSGEEEDLLI CKDCNAKAHP SCMRYSADLA RRSRMSPWQC IDCKTCYICD DSGDAETLLF
CDACDKGYHM ACHEPAVTHK PLGKWVCQRC KDDMGMEIDE ELMDTAEIGP HKSPPQLFNG
MVERKQTKQT SGDRKSPTVA TPTQPESACL PEQSASVMEA QQKKKPVAAA WAIPDVVGFI
KDVGFEKEAE AFQEQEIDGP AFLLLKRSDV LTGMSIKLGP ALKIYNHVMK VQTNTHPSL
//
