ID C3YJL2_BRAFL Unreviewed; 355 AA.
AC C3YJL2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 80.
DE RecName: Full=Transcription factor {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=BRAFLDRAFT_207916 {ECO:0000313|EMBL:EEN59319.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN59319.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN59319.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN59319.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
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DR EMBL; GG666520; EEN59319.1; -; Genomic_DNA.
DR RefSeq; XP_002603308.1; XM_002603262.1.
DR AlphaFoldDB; C3YJL2; -.
DR STRING; 7739.C3YJL2; -.
DR InParanoid; C3YJL2; -.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd14458; DP_DD; 1.
DR Gene3D; 1.20.140.80; Transcription factor DP; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR037241; E2F-DP_heterodim.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR038168; TF_DP_C_sf.
DR InterPro; IPR014889; Transc_factor_DP_C.
DR InterPro; IPR015648; Transcrpt_fac_DP.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12548; TRANSCRIPTION FACTOR DP; 1.
DR PANTHER; PTHR12548:SF9; TRANSCRIPTION FACTOR DP; 1.
DR Pfam; PF08781; DP; 1.
DR Pfam; PF02319; E2F_TDP; 1.
DR PIRSF; PIRSF009404; Transcription_factor_DP; 1.
DR SMART; SM01138; DP; 1.
DR SMART; SM01372; E2F_TDP; 1.
DR SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|RuleBase:RU003796};
KW Transcription {ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 129..214
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT DOMAIN 221..355
FT /note="Transcription factor DP C-terminal"
FT /evidence="ECO:0000259|SMART:SM01138"
FT COILED 223..250
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEN59319.1"
FT NON_TER 355
FT /evidence="ECO:0000313|EMBL:EEN59319.1"
SQ SEQUENCE 355 AA; 39969 MW; CF8D14A7566FE81B CRC64;
VGLIDTNGEL AGFVRSHQDQ NTSPTKGTVQ LLCFPSRIHT IGETIILPKT LGPANTPASP
MILQQSPARP TPVAQLVQVQ QSPARAQQTT YTTVVTDPNL IQVGGQVRKR THDFIEADFS
ESKRKKGEKG GKGLRHFSMK VCEKVQRKGT TSYNEVADEL VAEFSDPQRH LSPSDQIGNA
YDQKNIRRRV YDALNVLMAM NIISKEKKEI KWIGLPTNSA QECQNLELEK QRRIDRIKQK
QQQLQELILQ QIAFKNLVQR NKRMEQAGTG PPNQNSAIQL PFIIVNTSKK TVIDCSISND
KYEYLFNFDN TFEIHDDIEV LKRMGMAYGL ESGKCAPENL KIAKTLVPRA LEPYV
//
