ID C3YQ37_BRAFL Unreviewed; 518 AA.
AC C3YQ37;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE RecName: Full=Aminoglycoside phosphotransferase domain-containing protein {ECO:0000259|Pfam:PF01636};
GN ORFNames=BRAFLDRAFT_85744 {ECO:0000313|EMBL:EEN57675.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN57675.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN57675.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN57675.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- SIMILARITY: Belongs to the methylthioribose kinase family.
CC {ECO:0000256|ARBA:ARBA00010165}.
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DR EMBL; GG666539; EEN57675.1; -; Genomic_DNA.
DR RefSeq; XP_002601663.1; XM_002601617.1.
DR AlphaFoldDB; C3YQ37; -.
DR STRING; 7739.C3YQ37; -.
DR eggNOG; ENOG502QVM3; Eukaryota.
DR InParanoid; C3YQ37; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR002575; Aminoglycoside_PTrfase.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR34273; METHYLTHIORIBOSE KINASE; 1.
DR PANTHER; PTHR34273:SF2; METHYLTHIORIBOSE KINASE; 1.
DR Pfam; PF01636; APH; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 209..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..103
FT /note="Aminoglycoside phosphotransferase"
FT /evidence="ECO:0000259|Pfam:PF01636"
SQ SEQUENCE 518 AA; 56402 MW; 6AB16F1DED40327A CRC64;
MVSLTEQYIF TRPFLKDDPT NHSSEPIKAI LHLVHDDREL QSIVGKFKRL FLEKQESLVH
GDLHSGSILV RPTDGGVKVI DAEFAYIGPS ALDLGLLLAS YVFSYSAHKE KGNDGGDMTF
CELLCQAIHL TEQQRNSVVQ QKMPPTTRSR SRVSVKASTI STNSSWTSSE FLCAAVALGT
GVYGTVQQDL SALWQKGDIK SRLLLANHAV LVLVLSIAVL VTCGKLVSGL ASKVRRVRSS
TWRSSRENES SGVTKVFILA MLTGICACLV LYVTLCYLIA HPWLDISQTT FTTRLAASLA
VCLSTAAILV SLIVTSALLD QLLISFGLDP DQTNFALIVQ CITSNSAALM THLGLLSSMY
SLAWVSGEAG VQLWLQRIAL VLIGGPACLL EAVLLFWTIK KLTRMIISVV SQYVQKVIEI
MNAIRLSLPA MFFLSCLATS GAVYGVLFTE EKAPDDVIFA ALVVLTAMAI AVNVGLGLWL
VYDILPLDNQ EQIQQGGVDF MAALLMEMPF LPQQPKES
//
