ID C3YRE2_BRAFL Unreviewed; 1230 AA.
AC C3YRE2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=CUB domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=BRAFLDRAFT_214610 {ECO:0000313|EMBL:EEN57139.1};
OS Branchiostoma floridae (Florida lancelet) (Amphioxus).
OC Eukaryota; Metazoa; Chordata; Cephalochordata; Leptocardii; Amphioxiformes;
OC Branchiostomatidae; Branchiostoma.
OX NCBI_TaxID=7739;
RN [1] {ECO:0000313|EMBL:EEN57139.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 {ECO:0000313|EMBL:EEN57139.1};
RC TISSUE=Testes {ECO:0000313|EMBL:EEN57139.1};
RX PubMed=18563158; DOI=10.1038/nature06967;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U.,
RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K.,
RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J.,
RA Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J., Kapitonov V.V.,
RA Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A.,
RA Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T.,
RA Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H.,
RA Satoh N., Rokhsar D.S.;
RT "The amphioxus genome and the evolution of the chordate karyotype.";
RL Nature 453:1064-1071(2008).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; GG666547; EEN57139.1; -; Genomic_DNA.
DR RefSeq; XP_002601127.1; XM_002601081.1.
DR AlphaFoldDB; C3YRE2; -.
DR STRING; 7739.C3YRE2; -.
DR eggNOG; KOG1388; Eukaryota.
DR InParanoid; C3YRE2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00055; EGF_Lam; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR46376:SF2; DISTRACTED, ISOFORM B; 1.
DR PANTHER; PTHR46376; LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF13418; Kelch_4; 1.
DR Pfam; PF13854; Kelch_5; 1.
DR Pfam; PF00053; Laminin_EGF; 2.
DR Pfam; PF01437; PSI; 1.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00180; EGF_Lam; 2.
DR SMART; SM00612; Kelch; 3.
DR SMART; SM00423; PSI; 4.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1078..1102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..142
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 172..206
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 868..913
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DISULFID 176..186
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 196..205
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 885..894
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 897..911
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEN57139.1"
SQ SEQUENCE 1230 AA; 134513 MW; 8031EDC2736E4167 CRC64;
NCVHGQCSEG ECVCDRGWNG DRCQYCGGRF RLTSNSGVIT DGPSNYTTVT KCTWLIDSGR
VGSTIRLRFN EFATECSWDH VYVYDGDSVF APLVATFSGL MTHLQPNRTS YELTTTSGYA
YLHFFSDAAY NMSGFNISYS LNACPLDCSG HGTCDSSSVC TCQQGWKGDA CNEPACPNLC
SNHGHCDYSG TLDCICNPGY RGADCSACSP AGDDCNHTDA QVVWERERPG LPGRSSHVCV
QQDVWMWIVG GYTFSSASFY NLIRYHLVEN TWSPVTPTTA VNPVERYGHT AVLYGDKIIM
FGGLVEGRVV TNETWAFDTV LHQWEQLSQA GLALEGHSAN IVDSKGIIFE LLFDLTATDK
WRSVETSGAA VSGSYGHTSV YDQVSGKIYV HGGYTVLKKN RYTVSDFTYA FDPETGQWCV
GKCSGVPRYL HSAVTIGGFM LVFGGNTHND TSTSSGAKCF SADYLAYDLE CHSWQHLPGP
GPDYQPHRFG HSAIVLNRTM VVFGGFNSVL LGDILKYSTG DCSMIEEEEV CTSSQPGAVC
VWTEVGCMDR QAAAQLGETR QCPPITGSCG TFSDCGTCVT SIHTCQWCTD DSTCKTTCEG
TEAVSNLQSC PAVPVCNTFN CNDCQDRPGC HWQSEECKQG MKAIFHLFGG IMPQRLYIND
CSMQHSNSWL YCISSCQHCL KLSSPYPLQS TFNLGGSGYT VLRFLLFAGG ISDQLLCKVQ
VNCTGHGQGF AYKNAVSLST AEVAPCKQPC SHRLDIVNCT QADCMWCSNQ KRCVDSNAYV
PSFPYGQCLE WCTKADGCPG ECSSLRTCEV CQQQPECGWC DDGSQTGLGG CVEGSSAGPM
VGGSDGDFQL NTTVCPASRW YFTSCPECQC NGHSTCNNTN VCQQCQDLTQ GTHCEQCVPG
YYGDATNGGN CTVCQCHGHA DYCNAQNGDC FCNTKGIIGK GCDRCDVSHR YFGDAVTGTC
YYDLLIDYQF TFNLSKSDEK YYTGINFMNI PSHASRDVTF TINTSAMATM NITIATSDPG
GKVLVSAADF TFYKSVYSHV DYSFGSSQNT TFYVIVYNFT TPFWLQVTFS QHGSILDLVQ
FFVTFFSCFL SLLLVAGIFW KVKQRVDTFR RRREMIIEMA QMASRPFSKV MLEMEINTEP
PDGVNKRKQR RPGAISLEPL AGNKAAVLSV FMHLSTGDSS QPAVGHTGLA VGSTLVAVEH
SSKPAEGKDK QPMSLWHRKH HSPTHIGTCI
//
